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Completed

NCT Number: NCT00646997

Impact of Left Atrial Function on Postoperative Atrial Fibrillation

We aimed to demonstrate the impact of left atrial functions which were evaluated by three different echocardiographic modalities , on postoperative atrial fibrillation.

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Key information

Age range

30 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Istanbul, 34381, Turkey (Türkiye)

About this study

Postoperative atrial fibrillation after coronary artery bypass greft operation (CABG) is major complication with a prevalence of 10-50%. Although the men mechanism is not known, in recent studies, age and left atrial function have been demonstrated as the most responsible factors. Velocity vector imaging (VVI) is a new modality which may give accurate and detailed information on both left atrial segmental and global function. In this study, our aim was to assess preoperative left atrial function by using three different echocardiographic modalities, VVI, tissue Doppler imaging and conventional echocardiography and evaluate the relation between the left atrial functions and the development of post-operative atrial fibrillation after CABG.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1Coronary artery disease evidenced by coronary angiography
  • 2Patients with a decision of undergoing elective coronary artery bypass greft operation
  • 3Sinus rhythm in electrocardiography

Exclusion criteria

  • 1Rheumatic valve disease
  • 2Having prosthetic valve
  • 3CABG accompanied by other cardiac interventions (such as valvular surgery, ASD closure...etc)
  • 4Left ventricular l ejection fraction <40%
  • 5Mild to moderate mitral stenosis or regurgitation
  • 6Having atrial fibrillation or a history of atrial fibrillation attach during the last two weeks.
  • 7Congenital heart disease
  • 8Chronic liver disease
  • 9Chronic renal disease
  • 10Malignancy

Treatment and study plan

Primary outcomes

  1. Velocity vector imaging derived left atrial segmenter function, Tissue doppler derved left atrial segmenter function, conventional analysis of atrial function by 2D and pulsed wave echocardiography.

    Time frame: April 2008

Sponsors and collaborators

Lead sponsor

Florence Nightingale Hospital, Istanbul

Other

Registry information

Official study title

Impact Of Velocity Vector Imaging, Tissue Doppler Imaging, Conventional Echocardiography And P Wave Dispertion In Evaluating Post-Operative Atrial Fibrillation After Coronary Bypass Graft Surgery

Important dates

Study start
2008
Primary completion
2008
Study completion
2008
First posted
Mar 31, 2008
Registry last updated
Jun 30, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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