Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso)

The purpose of this is to determine the impact of intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) on the morbidities associated with malaria in pregnant women and newborns in rural peri-urban areas of Bobo-Dioulasso, 5 years after its implemented.

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Key information

Conditions

Malaria, Pregnancy Infections Malaria Mosquito-Borne Diseases Parasitic Diseases Protozoan Infections Vector Borne Diseases

Sex eligibility

Female

Study type

Observational

Primary location

Institut Supérieur des Sciences de la Santé/Université Polytechnique de Bobo-Dioulasso

Bobo-Dioulasso, Houet, 1091, Burkina Faso

About this study

Malaria in pregnant women is a crucial issue in Burkina Faso. Faced with this problem, a strategy based on the use of treated nets and intermittent preventive treatment (IPT) based on sulfadoxine-pyrimethamine (SP) was adopted in 2005. Five years after its implementation, the investigators will check whether this strategy is still effective in the preventing maternal and congenital malaria on the one hand and maternal anemia, low birth weight and prematurity on the other hand.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Residing in the health area of Lafiabougou or secteur 24
Having agreed to give free and informed consent

Exclusion criteria

Bleeding from during the pregnancy
eclampsia

Treatment and study plan

Primary outcomes

Peripheral and placental malaria

Time frame: Peripheral malaria : at antenatal clinics and at delivery. Placental malaria: at delivery

The investigators will check if pregnant women have any malaria parasites by making a finger prick thick respectively at antenatal clinics and at delivery. A placental thin smear will be made at delivery.

Secondary outcomes

Maternal anemia, congenital malaria,low birth weight, prematurity.

Time frame: Maternal anemia: at antenatal clinics and at delivery. Congenital malaria: at delivery. Low birth weight: at delivery. Prematurity: at delivery.

The investigators will check pregnant women haemoglobin level.A level< 11g/dl will be considered as anemia.

Congenital malaria will be assessed through cord blood smear. Birth weight <2500g will be considered as low birth weight. Prematurity designs any birth before 37 gestation weeks.

Sponsors and collaborators

Lead sponsor

Université Polytechnique de Bobo-Dioulasso

Other

Registry information

Official study title

Impact of Intermittent Preventive Treatment (IPT) With Sulfadoxine-pyrimethamine (SP) on the Morbidities Associated With Malaria in Pregnant Women and Newborns in Peri-urban Areas of Bobo-Dioulasso, 5 Years After Its Adoption by the National Program for Fight Against Malaria in Burkina Faso.

Important dates

Study start: 2010
Study completion: 2011
First posted: Dec 7, 2010
Registry last updated: Jun 18, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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