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Completed

NCT Number: NCT07367386

Impact of Increasing BMI on the Success of Neuraxial Blocks in Class III Obese Parturients

This study seeks to compare the success rates, feto-maternal outcomes, and complications associated with different neuraxial blocks in Class III obese parturient undergoing cesarean section

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Key information

Conditions

Neuraxial Blocks Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Women's Wellness and Research Center

Doha, Qatar

About this study

This was a retrospective cohort study. The data was obtained from electronic medical records of the eligible participants.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > or equal to 18 years
  • BMI ≥ 45 kg/m²
  • Gestational age ≥ 28 weeks

Exclusion criteria

  • Age < 18 years
  • BMI < 45 kg/m²
  • History of venous thromboembolism or arterial disease (e.g., DVT, PE, angina, MI, or stroke)
  • Severe active lung, cardiovascular, renal, or liver disorders; autoimmune disease; or hemoglobinopathies
  • Hereditary or acquired thrombophilia (e.g., Factor V Leiden mutation or antithrombin deficiency)
  • In utero fetal demise (IUFD)
  • Failed operative vaginal delivery
  • Cesarean for the second twin or multiple pregnancies (triplets or higher)
  • IVF pregnancy
  • Intraoperative bleeding>1500mL
  • Emergency cesarean section (Category I)
  • Presence of large uterine fibroid ≥10 cm

Treatment and study plan

Neuraxial anesthesia

Procedure

Single-shot spinal anesthesia

Primary outcomes

  1. Failed neuraxial block

    Time frame: From onset of block until surgery completion

    Determine the occurrence of the conversion to general anesthesia

Secondary outcomes

  1. Maternal adverse events

    Time frame: From onset of blockade until surgery completion

    Determine the incidence of maternal hypotension, bradycardia, high-spinal (above T1 level), level of blockade higher than T4, post-dural puncture headache

  2. Fetal outcomes

    Time frame: At one and five minutes after birth

    Apgar score

Sponsors and collaborators

Lead sponsor

Mariah Arif

Other Gov

Registry information

Official study title

Evaluating the Impact of Increasing BMI on the Success of Neuraxial Blocks in Class III Obese Parturients: A Retrospective Cohort Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jan 26, 2026
Registry last updated
Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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