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NCT Number: NCT06469957

Impact of Hospital Pharmacist on Drug Management in Patients With Bronchopulmonary Cancer

This is a prospective, non-interventional study to evaluate impact of hospital pharmacist on drug management in patients (only questionnaires) with bronchopulmonary cancer treated by Chemotherapy and/or Immunotherapy or Oral targeted therapy. The primary objective of the study is to evaluate the number of unscheduled consultations/hospitalizations during 6 months.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU d'Orléans

Orléans, 45067, France

About this study

Currently, several treatments can be used for bronchopulmonary cancers: targeted oral therapy (OCT), oral chemotherapy, iv chemotherapy, iv immunotherapy. These therapies are rather unknown to community pharmacy and induce several adverse effects and drug interactions. These treatments require collaboration between different professionals (community and hospital pharmacists) in order to allow follow up and security in patient supportive care.

In our context of shortage of care staff, with a polymedicated and elderly population, we would like to assess the impact of hospital pharmacist in the drug management for patient with bronchopulmonary cancers treated by these therapies.

Other French studies (Lille, Angers, Tours) involving hospital pharmacists were carried out and aimed to evaluate the number of pharmaceutical interventions carried out without assessing the impact on the patient. In addition, no study concerns the Center Val de Loire region.

The aim of the study is to impact of hospital pharmacist (interview) on the number of unscheduled consultations/hospitalizations.

This is a prospective, non-interventional study to evaluate impact of hospital pharmacist on drug management in patients with bronchopulmonary cancer. Participants will be included after being informed and after obtaining no opposition to participate. Data collection sheet will be performed by hospital pharmacist at inclusion. Participants will be treated according to standard of care for cancer treatment. An interview will be performed 1 month, 3 months and 6 months after inclusion between hospital pharmacist and participant to obtain information's on cancer treatments (questionnaires). These interviews will be performed by phone or when the patient comes to the hospital for a follow-up consultation as part of the treatment of his cancer (standard of care).

A total of 60 participants will be included in this study based on 1) the number of patients received a novel cancer treatment in the center during 12 months and 2) considered eligibility criteria, pharmacist availability and patients consent.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female ≥ 18 years
  • Patient without cognitive impairments
  • Patient with bronchopulmonary cancer
  • Patient treated by chemotherapy, immunotherapy or oral targeted therapy

Exclusion criteria

  • Patient informed and opposed to participate
  • Language barrier and lack of translator
  • Patient under guardianship, curatorship or deprived of liberty
  • Pregnant or breastfeeding women
  • Participation in any drug clinical drug trials
  • Patient with no insurance

Treatment and study plan

Questionnaires and data collection sheet

Other

Questionnaires

Primary outcomes

  1. Impact of hospital pharmacist (interview) on the number of unscheduled consultations/hospitalizations.

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Number of unscheduled consultations or hospitalizations during the follow up phase

Secondary outcomes

  1. Impact of hospital pharmacist (interview) on cancelled consultations/hospitalizations rate

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Number of cancelled consultations/hospitalizations

  2. Impact of hospital pharmacist (interview) on treatment observance (number of dispensation)

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Number of treatment dispensation

  3. Impact of hospital pharmacist (interview) on treatment observance (gap between dispensation)

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Gap between each treatment dispensation

  4. Impact of hospital pharmacist (interview) on adverse effects

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Number of adverse effects (follow up phase of 6 months)

  5. Impact of hospital pharmacist (interview) on adverse effects leading to interrupted or withdrawn treatment

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Number of adverse effects leading to interrupted or withdrawn treatment

  6. Impact of hospital pharmacist on pharmaceutical intervention

    Time frame: From enrolment to the end of the follow up phase (6 months)

    Number of pharmaceutical interventions (eg. inappropriate prescription, drug interactions)

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Régional d'Orléans

Other

Registry information

Official study title

Impact of Hospital Pharmacist on Drug Management in Patients With Bronchopulmonary Cancer Treated by Chemotherapy and/or Immunotherapy or Oral Targeted Therapy

Acronym: IMPACTO

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 24, 2024
Registry last updated
Mar 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.