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NCT Number: NCT06623799

Impact of Help-Seeking Behaviors on Allergic Rhinitis and Mental Health: A Longitudinal Study

This study explores how help-seeking behaviors for both emotional well-being and allergies impact the management of allergic rhinitis, asthma, and mental health symptoms, including anxiety and depression. The research involves a retrospective and longitudinal analysis of patients who sought treatment for allergic rhinitis and mental health concerns. The goal is to highlight the importance of integrating mental health care into allergy treatment plans to improve overall patient outcomes.

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Key information

Conditions

Mental Health Conditions Allergic Behavior Help-Seeking Behavior Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Nose Diseases Otorhinolaryngologic Diseases Personal Satisfaction Psychological Well-Being Respiratory Hypersensitivity Respiratory Tract Diseases Rhinitis Rhinitis, Allergic Social Behavior

Age range

4 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

This study aims to investigate the impact of help-seeking behaviors (HSB) on allergic rhinitis (AR), asthma control, and mental health outcomes, such as anxiety and depression, using both retrospective and longitudinal data. The study examines patients who have been diagnosed with AR and mental health conditions to assess how seeking professional help for allergies, emotional well-being, or both influences symptom control and quality of life.

The research analyzes data from a diverse patient population to evaluate the effects of AR medications (intranasal steroids, antihistamines, decongestants, and leukotriene blockers) on both AR and mental health symptoms. Additionally, it explores the role of help-seeking behaviors in improving symptom management, specifically through the use of validated tools like the SNOT-22 for AR and the PHQ-GAD16 for mental health.

The study emphasizes the importance of integrating mental health screening and support into the treatment of allergic rhinitis and asthma. By analyzing real-world data, the research seeks to provide insights into how coordinated care approaches can enhance patient outcomes and inform future clinical practices.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults (aged 18 years or older) Patients actively receiving care in a primary care setting. Patients who have provided informed consent for their health data to be included in the research repository.

Exclusion criteria

Patients who have not provided informed consent for their health data to be included in the research repository.

Patients diagnosed with chronic conditions outside the scope of allergic rhinitis, asthma, or mental health conditions (anxiety, depression).

Patients with severe mental health disorders or comorbidities that are unrelated to the conditions of interest (e.g., schizophrenia, bipolar disorder, etc.).

Treatment and study plan

Primary outcomes

  1. Change in Allergic Rhinitis Symptom Severity (SNOT-22 Score)

    Time frame: baseline and yearly follow-up for up to 5 years

    This outcome measures the long-term change in allergic rhinitis symptom severity over several years using the Sinonasal Outcome Test (SNOT-22). The SNOT-22 is a validated tool that assesses the impact of sinonasal conditions on quality of life. The study will track the effects of help-seeking behaviors for both allergies and mental health (anxiety and depression) on allergic rhinitis symptom control, examining changes in SNOT-22 scores over multiple follow-up periods. Scores range from 0 to 110, with higher scores indicating worse symptoms and lower quality of life.

Secondary outcomes

  1. Change in Depression Symptoms (PHQ-9 Score)

    Time frame: Baseline and yearly follow-up for up to 5 years

    This outcome measures the change in depressive symptoms using the Patient Health Questionnaire (PHQ-9). The PHQ-9 is a validated tool to assess the severity of depression. Scores range from 0 to 27, with higher scores indicating more severe depressive symptoms. The study will assess how help-seeking behaviors for both allergies and mental health impact the severity of depressive symptoms over time.

  2. Change in Anxiety Symptoms (GAD-7 Score)

    Time frame: Baseline and yearly follow-up for up to 5 years

    This outcome measures the change in anxiety symptoms using the Generalized Anxiety Disorder Scale (GAD-7). The GAD-7 is a validated tool to assess the severity of anxiety. Scores range from 0 to 21, with higher scores indicating more severe anxiety symptoms. The study will assess how help-seeking behaviors for both allergies and mental health impact the severity of anxiety symptoms over time.

Other outcomes

  1. Effect of Help-Seeking Behaviors on Symptom Control and Quality of Life

    Time frame: Baseline and yearly follow-up for up to 5 years

    This outcome evaluates the effect of help-seeking behaviors (seeking help for emotional well-being, allergies, or both) on overall symptom control and quality of life. The study will explore the relationship between help-seeking behaviors and improvements in allergic rhinitis symptoms (SNOT-22) and mental health outcomes (PHQ-9, GAD-7). Scores from each scale will be analyzed separately to assess the impact of help-seeking behaviors on these specific health outcomes.

Study contacts

Contact information is provided by the study sponsor or research team.

Marcos A Sanchez-Gonzalez, MD, PhD

CONTACT

[email protected]

850-559-7676

Troy Grogan

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

QHSLab, Inc.

Industry

Registry information

Official study title

Impact of Help-Seeking Behaviors on Allergic Rhinitis, Asthma Control, and Mental Health: A Retrospective and Longitudinal Analysis of Allergy Medication Use

Important dates

Study start
2020
Primary completion
2027
Study completion
2027
First posted
Oct 2, 2024
Registry last updated
Feb 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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