Impact of General Anaesthetics on Excitability of the Peripheral Sensory Nerve

The aim of this study is to investigate the effect of general anaesthetics on nerve excitability. We use the method of threshold tracking to measure selected parameters of nerve excitability.

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Key information

Conditions

Scheduled for Surgery

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Zurich

Zurich, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

German speaking patients scheduled for surgery under general anaesthesia.

Weight 50 - 100 kg signed informed consent

Exclusion criteria

1. known peripheral neuropathy 2. Diabetes mellitus 3. Neuro-psychiatric Diagnosis 4. pregnant/ breast-feeding women 5. congestive heart disease 6. more than 2 risk factors (out of 4) for PONV (female, non-smoker, known PONV, opioids postoperatively) 7. participants of other studies 8. inability of verbal expression

Treatment and study plan

Nerve excitability measurement

Behavioral

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Important dates

Study start: 2008
Study completion: 2008
First posted: Jun 12, 2008
Registry last updated: Jun 3, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.