Impact of Fluid Resuscitation Protocol on the Incidence of Reoperation for Bleeding After Emergency Cardiopulmonary Bypass Grafting

This is a retrospective data analysis of patients that underwent elective or emergency cardiopulmonary bypass. Resternotomy due to bleeding is frequent after sternotomy. Also due to implementation of Argipressin into clinical practice fluid resuscitation protocol has changed to more vasopressors and less fluid within the past five years. The investigators want to explore the influence of volume resuscitation protocol on incidence of rethoracotomy during the past twenty years.

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Key information

Conditions

Resternotomy

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients that underwent elective or emergency aortocoronary bypass at the University Hospital Basel between 2009 and 2020.

Exclusion criteria

None.

Treatment and study plan

Assessment of reason for resternotomy

Other

No intervention is performed. Reasons for resternotomy (coagulation, fluid balance and other) are retrospectively assessed.

Assessment of reason for avoidance of resternotomy

Other

No intervention is performed. Reasons for avoidance resternotomy (coagulation, fluid balance and other) are retrospectively assessed.

Primary outcomes

Resternotomy

Time frame: 7 days

Resternotomy yes or no after elective or emergency aortocoronary bypass

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Registry information

Acronym: Volu-CABG

Important dates

Study start: 2009
Primary completion: 2021
Study completion: 2024
First posted: Aug 31, 2020
Registry last updated: Apr 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.