Impact of Fatty Stimuli on Cerebral Activity in Anorexia Nervosa: a Multi-sensory Approach

Inclusion criteria

• Person affiliated or entitled to a social security scheme
• Person having received informed information on the study and having co-signed, with the investigator, a consent to participate in the study
• female person
• Person affiliated or entitled to a social security scheme
• Over 18 years'old
• Knowing how to read and write French
• Patient diagnosed with anorexia nervosa according to DSM-5 criteria for at least 5 years (HAS criteria). Failure of prior outpatient or/and hospitalization care over the last 12 months: stable or falling low BMI, unmodified food restriction, continued fear of weight gain, disturbances in the perception of body image
• BMI < 18.5 kg/m² for volunteers in a state of constitutional thinness. The absence of eating disorder and the absence of restriction to DEBQ questionnaires. Fertility preserved.
• For volunteers of normal weight: 18.5 kg/m² < BMI < 25 kg/m²

Exclusion criteria

• Pregnant women, parturient, nursing mothers;
• Persons deprived of their liberty, hospitalized without consent, hospitalized for purposes other than research;
• Minors
• Refusal of the study by the participant
• Person incapable of giving informed consent
• Artificial nutrition
• Associated organic damage favoring undernutrition: other chronic diseases (digestive, infectious, endocrine, pulmonary, cardiac, neurological), neoplasms, etc.
• Abuse of psychoactive substances except tobacco
• Characterized depressive episode, psychosis
• Score less than 14 on the Edinburgh laterality questionnaire.
• Contraindications to MRI or allergy to one of the components of the olfactory and taste tests
• Smokers
• Smell or taste alterations