Impact of Erector Spinae Plane Block on Systemic Immune-inflammation Index

The primary objective of the study is to determine whether there is a relationship between postoperative SII and erector spinae plane block application. If data emerges indicating a more suppressed inflammatory response in patients undergoing block, widespread use of this block in the specified patient group would reflect the clinical significance of the study.

The searches did not uncover any studies investigating the effects of trunk blocks, such as erector spinae plane block, on postoperative systemic inflammatory response, indicating that this study could make a significant contribution to the literature.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Systemic Immune-inflammatory Index Breast Conserving Surgery Erector Spinae Plane Block

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Basaksehir Cam ve Sakura City Hospital

Istanbul, Turkey (Türkiye)

About this study

Because the study will be conducted retrospectively, it carries no potential risks.

If it can be demonstrated that blocking has a suppressive effect on the inflammatory response, the main expected benefit of the study is its widespread use to improve postoperative outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ASA score ≤ 3, breast-conversing surgery, age > 18 -

Exclusion criteria

ASA score > 3, reoperation, surgical wound infection, chemotherapy in less than 2 weeks, bening lesions

Treatment and study plan

Erector Spinae Plane Block

Procedure

A standardized perioperative care management protocol is applied for all breast-conserving surgery procedures in our department. All patients are informed about ESPB and offered its application preoperatively. Patients who accept the procedure receive ESPB (preoperatively, in the sitting position, at the level of ipsilateral T4 vertebra, USG guided, out-of-plane approach) while those who refuse are subjected to routine intravenous analgesia protocols. All blocks were performed by an anesthesiologist experienced in the application of truncal blocks and 20 cc 0.5% bupivacaine (within the safe dose range for all patients to be used according to their weight) are injected and its spread is visualized under USG.

Primary outcomes

systemic immune-inflammation index

Time frame: 7 days after surgery

Platelet count × Neutrophil count / Lymphocyte count

Sponsors and collaborators

Lead sponsor

Taner Abdullah

Other

Registry information

Official study title

Impact of Erector Spinae Plane Block on Systemic Immune-inflammation Index in Breast-conserving Surgery: A Retrospective Cohort Study

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Aug 22, 2025
Registry last updated: Aug 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed