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NCT Number: NCT07332949

Impact of Dialysis on Sexuality.

Sexuality is an essential dimension of quality of life and is frequently impaired in patients with end-stage chronic kidney disease undergoing hemodialysis. Sexual dysfunctions-including erectile dysfunction, reduced sexual desire, and difficulties with arousal or orgasm-are highly prevalent in this population. These disorders have multifactorial origins, involving hormonal disturbances, comorbidities, treatment-related side effects, chronic fatigue, and the psychological and relational impact of long-term illness.

Despite their frequency, sexual health issues are rarely addressed in routine dialysis care. This is largely due to time constraints during consultations, insufficient training of healthcare professionals, and persistent social and cultural taboos. In addition, the existing scientific literature remains limited, often outdated, and predominantly focused on male patients. Data concerning women, sexual diversity, body image, and couple-related aspects are scarce. Standard kidney disease-specific quality-of-life instruments, such as the KDQOL questionnaire, provide only a minimal assessment of sexuality, with a single item related to sexual desire.

The aim of this study is to provide a contemporary and comprehensive assessment of the impact of dialysis on sexual quality of life. By documenting sexual function and sexual complaints in patients undergoing dialysis, this study seeks to improve understanding of patients' experiences and to facilitate communication between patients and healthcare professionals. Ultimately, the findings are intended to support better integration of sexual health into routine nephrology care and to contribute to improved clinical practices in the field of sexual health.

This study is designed as a cross-sectional survey conducted among patients undergoing dialysis at the Groupe Hospitalier Privé Ambroise Paré-Hartmann in the Paris area. Eligible patients are informed about the study during a dialysis session by a healthcare professional (dialysis nurse, nephrologist, or physiotherapist specialized in sexology). Participants complete a self-administered questionnaire during their dialysis session, including the Male Sexual Health Questionnaire (MSHQ) for men and the Female Sexual Function Index (FSFI) for women. Additional questions addressing medical history and body image perception are included. The estimated completion time for the questionnaire is approximately 20 minutes.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ambroise Paré - Hartmann Private Hospital Group

Neuilly-sur-Seine, Île-de-France Region, 92200, France

Location status: Recruiting

Location contact

Nicolas Benichou, MD

CONTACT

[email protected]

0146415079 ext. +33

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient > 18 years,
  • Treated with chronic dialysis (hemodialysis or peritoneal dialysis) for at least 6 months.

Exclusion criteria

  • Major cognitive or psychiatric disorders that make understanding or completing the questionnaire difficult.
  • General health condition not allowing participation without significant discomfort or excessive fatigue.
  • Opposition by the patient.

Treatment and study plan

Questionnaire on sexuality

Other

The patients will receive the following questionnaires to complete during the dialysis session:

  • MSHQ (Male Sexual Health Questionnaire) for men
  • FSFI (Female Sexual Function Index) for women Additional questions addressing medical history and body image perception are included.

Primary outcomes

  1. Sexual quality of life

    Time frame: At baseline, during a dialysis session

    The MSHQ questionnaire for men consists of 25 questions, minimum score: 25, maximum score: 125. A higher score on this scale indicates better sexual function.

  2. Sexual quality of life

    Time frame: At baseline, during a dialysis session

    The FSFI questionnaire for women consists of 19 questions, minimum score: 2, maximum score: 36. A higher score on this scale indicates better sexual function.

Secondary outcomes

  1. Body perception

    Time frame: At baseline, during a dialysis session

    Questionnaire adapted from the Body Image Scale consisting of 4 questions, minimum score: 0, maximum score: 12. A higher score indicates a poorer body image.

Study contacts

Contact information is provided by the study sponsor or research team.

Nicolas Benichou, MD

CONTACT

[email protected]

0146415079 ext. +33

Sponsors and collaborators

Lead sponsor

CMC Ambroise Paré

Other

Registry information

Acronym: SEXODIA

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jan 12, 2026
Registry last updated
Feb 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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