Sohag University Hospital
Sohag, Egypt
Location contact
Mahmoud Ibrahim Yousef, Associate Professor
CONTACT
Mohamed Mahmoud Rashad, Master Degree
CONTACT
Not Yet Recruiting
NCT Number: NCT07354958
Impact of Diabetes-Related Metabolic Derangements on Clinical Outcomes in Hospitalized Patients With Chronic Kidney Disease
This observational study will collect clinical and laboratory information from hospitalized patients with chronic kidney disease to identify diabetes mellitus and selected metabolic findings during hospitalization
Not Yet Recruiting
Trial opening soon.
Get NotifiedKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
Hospitalized adult patients with chronic kidney disease will be included in this observational study. Information routinely recorded during hospitalization will be collected. This information will include the presence of diabetes mellitus and laboratory values related to blood glucose levels, electrolyte levels, and acid base balance. No study related interventions will be performed.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Age greater than or equal to 18 years
- Known chronic kidney disease, defined as baseline estimated glomerular filtration rate less than 60 milliliters per minute per 1.73 square meters for at least 3 months, or documented chronic kidney disease stage 3 to 5 by prior medical records
- Hospitalized for any medical reason
- Consent provided
Exclusion criteria
- Acute single episode of reversible acute kidney injury with previously normal renal function (no established chronic kidney disease)
- Admission for palliative care or expected survival less than 24 hours
- Pregnancy
Treatment and study plan
Primary aim 1. To assess the frequency of diabetes mellitus among hospitalized CKD patients. 2. To evaluate the frequency and types of metabolic abnormalities (e.g., hypoglycemia, diabetic ketoacidosi
BehavioralPrimary aim
- To assess the frequency of diabetes mellitus among hospitalized CKD patients.
- To evaluate the frequency and types of metabolic abnormalities (e.g., hypoglycemia, diabetic ketoacidosis/ hyperosmolar states, metabolic acidosis, dyslipidemia, electrolyte imbalance) in diabetic CKD patients.
Secondary aim
- To evaluate the association between diabetes and diabetes-related metabolic derangements in-hospital adverse outcomes (major cardiovascular events, ICU admission, length of stay, infection rate, need for dialysis and mortality) among hospitalized patients with CKD.
Primary outcomes
-
In-Hospital Mortality
Time frame: From admission until hospital discharge, assessed over a 6-month study enrollment period.
Patient death from any cause occurring during the hospitalization period
-
New Requirement for In-Hospital Renal Replacement Therapy
Time frame: From admission until hospital discharge, assessed over a 6-month study enrollment period.
Initiation of dialysis in a patient who was not receiving renal replacement therapy at the time of hospital admission
-
Incidence of a Major In-Hospital Cardiovascular Composite Event
Time frame: From admission until hospital discharge, assessed over a 6-month study enrollment period.
A composite outcome defined as the first occurrence of any of the following during the hospitalization: myocardial infarction, stroke, or new-onset heart failure requiring inotropic support or mechanical ventilation
Study contacts
Contact information is provided by the study sponsor or research team.
Mahmoud Ibrahim Yousef, Associate Professor
CONTACT
Mohamed Mahmoud Rashad, Master Degree
CONTACT
Sponsors and collaborators
Lead sponsor
Sohag University
Other
Registry information
Important dates
- Study start
- 2026
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Jan 21, 2026
- Registry last updated
- Jan 21, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.