Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review

This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health. The review focuses on key outcomes such as preterm birth, maternal complications, and neonatal health, utilizing comprehensive literature from peer-reviewed journals. By analyzing existing studies, we aim to identify trends and gaps in research regarding COVID-19 and pregnancy. This review is intended to inform healthcare providers and pregnant individuals about potential risks and considerations during the pandemic.

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Key information

Conditions

COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Maternal Health Neonatal Health Nidovirales Infections Pneumonia Pneumonia, Viral Pregnancy Outcomes RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Sex eligibility

Female

Study type

Observational

Primary location

Zahedan University of Medical Sciences

Zahedan, Sistan and Baluchestan, Iran

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Pregnant individuals diagnosed with COVID-19.
Studies reporting pregnancy outcomes related to COVID-19 published between January 2020 and the present.
Articles that include quantitative data on maternal and fetal outcomes.

Exclusion criteria

Studies that do not report on COVID-19-related pregnancy outcomes.
Non-peer-reviewed articles or grey literature.
Research focusing on non-pregnant populations.

Treatment and study plan

Systematic Review of COVID-19's Impact on Pregnancy Outcomes

Other

This study is a systematic review of existing literature that examines the effects of COVID-19 on pregnancy outcomes, including maternal health, neonatal health, and obstetric complications. It synthesizes data from various studies to provide an overview of the potential risks associated with COVID-19 infection during pregnancy. This intervention does not involve any new clinical trials or direct patient interaction.

Primary outcomes

Impact of COVID-19 on Maternal and Neonatal Outcomes

Time frame: The review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.

This primary outcome measure evaluates the various maternal and neonatal outcomes associated with COVID-19 infection during pregnancy. Key metrics include rates of maternal morbidity, neonatal morbidity, preterm birth, low birth weight, and any documented complications during pregnancy, labor, and delivery. The systematic review aims to synthesize data from available studies to provide a comprehensive understanding of these outcomes and their implications for clinical practice.

Secondary outcomes

Effects of COVID-19 on Pregnancy-Related Complications

Time frame: The review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.

This secondary outcome measure assesses the frequency and types of pregnancy-related complications associated with COVID-19. This includes conditions such as gestational hypertension, gestational diabetes, placental abruption, and other adverse effects that may arise during the pregnancy period. The review aims to analyze the incidence of these complications in pregnant individuals diagnosed with COVID-19 compared to non-infected counterparts, providing insights into how the virus may impact overall pregnancy health.

Sponsors and collaborators

Lead sponsor

Zahedan University of Medical Sciences

Other

Registry information

Official study title

A Systematic Review of COVID-19's Impact on Pregnancy Outcomes

Acronym: COVID-PREG

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Nov 6, 2024
Registry last updated: Nov 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed