Khyber Teaching Hospital
Peshawar, KPK, 25000, Pakistan
Location status: Recruiting
NCT Number: NCT07425249
Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort. Chewing gum, as a form of sham feeding, has been proposed to stimulate gut motility through vagal stimulation and increased gastrointestinal secretions. This randomized controlled trial aims to assess the effect of chewing gum on early recovery of gastrointestinal motility in patients undergoing open gastrointestinal surgery.
Interested in participating?
Request Info17 year–85 year
All sexes
Interventional
Not applicable
Peshawar, KPK, 25000, Pakistan
Location status: Recruiting
This prospective randomized controlled trial will evaluate whether chewing gum reduces the time to return of bowel function after gastrointestinal surgery. Ninety-six adult patients undergoing open gastrointestinal surgery will be randomly allocated into intervention and control groups using block randomization. The intervention group will receive glucose-containing chewing gum starting six hours postoperatively. Outcomes measured include time to first bowel sounds, passage of flatus, and defecation. Statistical analysis will assess differences between groups to determine the efficacy of chewing gum in preventing postoperative ileus.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants will chew glucose/carbohydrate-containing chewing gum for 15 minutes, three times daily, starting 6 hours after surgery and continuing for 48 hours or until the first passage of flatus or stool, in addition to standard postoperative care.
Time frame: Within 48 hours postoperatively
Time interval (in hours) from the end of surgery to the first postoperative passage of flatus, assessed by patient self-report and clinical evaluation.
Time frame: Within 48 hours postoperatively
Time interval (in hours) from the end of surgery to the first postoperative bowel movement (defecation), assessed by patient self-report and clinical evaluation.
Contact information is provided by the study sponsor or research team.
Dr Ali Raza, MBBS
CONTACT
Dr Munir Ahmed, FCPS
CONTACT
Khyber Medical University Peshawar
Other
Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients: A Randomized Controlled Trial at Khyber Teaching Hospital, Peshawar, Pakistan
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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