Impact of Caregiver Depression on Asthma in the Child

This study will examine if depression in a primary caregiver is associated with more hospitalization or ER visits in children with asthma. This study will also explore whether treatment for depression in the primary caregivers is associated with improvement in asthma in school-aged children.

Asthma is a very common childhood disorder of airway inflammation. The causes include environmental irritants, cold temperature, and infection in the respiratory tract, and emotional factors can contribute to symptom exacerbation. However, asthma is a disease that can be well controlled if there is proper medication compliance and careful control of environmental conditions.

Data suggests that psychiatric symptoms in the mothers of children with asthma are associated with more asthma related hospitalizations in children. Thus, we want to explore this question further using more specific diagnostic instruments in order to detect what types of symptoms are associated with increased asthma related service utilization. Also, we want to explore if effective treatment of the caregivers' symptoms is associated with decreased hospitalization and emergency room visits for the child.

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Key information

Conditions

Depressive Disorder, Major Asthma Bronchial Diseases Depressive Disorder Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Mental Disorders Mood Disorders Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

The University of Texas Southwestern Medical Center at Dallas

Dallas, Texas, 75235, United States

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Primary caregiver of a child currently hospitalized at Children's Medical Center of Dallas for an asthma exacerbation and between the ages of 5 and 16 years old
Male and female
English or Spanish Speaking
Between the ages of 18 and 70 years old
Caregivers with major depressive disorder will be offered treatment

Exclusion criteria

At risk for suicide defined by multiple suicide attempts (greater than or equal to 3 in the past), and/or current suicidal ideation with a well-formed plan or intent
Unlikely to attend follow-up appointments
Mentally retarded or suffer from other severe cognitive impairment
Pregnant or nursing, or women of childbearing age who will not use methods of birth control or abstinence during the study
Suffering from a severe or life-threatening medical illness which would make completion of the study unlikely
Suffering from treatment refractory depression defined by failing three adequate trials of antidepressants
Depression as part of bipolar disorder or schizophrenia or schizoaffective disorder, or current depression secondary to a medication or general medical condition, or with psychotic features

Treatment and study plan

Lexapro

Drug

Sponsors and collaborators

Lead sponsor

University of Texas Southwestern Medical Center

Other

Registry information

Official study title

Caregiver Psychiatric Symptomatology and it's Relationship to Service Utilization by Children With Asthma

Important dates

Study start: 2003
Primary completion: 2006
Study completion: 2006
First posted: Sep 22, 2005
Registry last updated: Aug 3, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed