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Completed

NCT Number: NCT02481024

Impact of Care Transition on Medication Adherence in Cardiac Patients

Background:

Medication adherence following acute coronary syndrome (ACS) is often sub-optimal. Poor adherence is associated with increased risk of rehospitalisation along with higher rates of morbidity and mortality. After a cardiac event, transitioning from hospital into primary care can be problematic if it is not organised or coordinated properly. Patients can often find themselves unprepared and lacking the necessary information for self-management of their disease. The impact of care transition on medication adherence has not been studied in ACS.

Objectives:

This study will explore how an ACS patients' journey from hospital into primary care affects medicines use. Further, to understand how medicine information is communicated and how this influences patient beliefs about medicines.

Methods:

This is an interview study with recently hospitalised ACS patients discussing medication beliefs, communication of medicine information and the challenges when transitioning from specialist to primary care. Patients will be recruited from Guy's and St Thomas' NHS Foundation Trust and telephone interviews will be scheduled 3-4 weeks post-discharge. An inductive thematic analysis will be used to identify, construct and analyse patterns in the data and to develop a framework analysis. Analysis will be an iterative process conducted in parallel with data collection to highlight when data saturation has been reached.

Dissemination:

The primary objective is to develop a pharmacist-led behaviour change intervention to improve rates of medication adherence following an ACS. The in-depth patient data collected in this current study will contribute to the design and development of the intervention. Understanding the research topic from the patients' perspective is a necessity when designing an intervention targeting behaviour change.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Guy's and St Thomas' NHS Foundation Trust

London, SE1 7EH, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • over 18 years of age
  • have a confirmed index diagnosis of ACS
  • have sufficient spoken English to partake in an interview

Exclusion criteria

  • under 18 years of age
  • lack the level of spoken English required to be interviewed

Treatment and study plan

Primary outcomes

  1. Patient experiences

    Time frame: 3-4 weeks after discharged from hospital

    Analysing patients' experiences of care transition and its impact on adherence and treatment beliefs. This will be done using thematic analysis to identify, construct and assess patterns in the qualitative data to develop a framework analysis.

Sponsors and collaborators

Lead sponsor

King's College London

Other

Registry information

Official study title

'Moving From Hospital to Home' - Exploring the Impact of Care Transition on Medication Adherence in Cardiac Patients: a Qualitative Study Protocol

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Jun 25, 2015
Registry last updated
Jan 18, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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