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Completed

NCT Number: NCT02928341

Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo

The aim of the study is to evaluate the impact of a large-scale urban water supply improvement intervention on cholera and other diarrhoeal diseases. The study uses a step wedge cluster randomised controlled trial (SWcRCT) to measure the effect of the intervention on cholera centre admission rates and confirmed cholera cases. A nested cohort study will examine changes in water-related practices following the intervention.

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Key information

Conditions

Cholera Bacterial Infections Bacterial Infections and Mycoses Diarrhea Gram-Negative Bacterial Infections Infections Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive Vibrio Infections

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre de Traitement du Cholera, Hôpital General de Reference d'Uvira, Sud-Kivu, République Démocratique du Congo

Uvira, South Kivu, Democratic Republic of the Congo

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Uvira resident admitted to the Uvira Cholera Treatment Centre in Uvira

Exclusion criteria

  • Any patients admitted during the period of intervention implementation in each cluster

Treatment and study plan

Improved water supply

Other

Primary outcomes

  1. Admission rate to the Uvira Cholera Treatment Centre

    Time frame: 36 months

Secondary outcomes

  1. Admission rate to the Uvira Cholera Treatment Centre of laboratory confirmed cholera cases

    Time frame: 36 months

Sponsors and collaborators

Lead sponsor

London School of Hygiene and Tropical Medicine

Other

Registry information

Official study title

Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal in Uvira, Democratic Republic of Congo

Important dates

Study start
2016
Primary completion
2021
Study completion
2021
First posted
Oct 10, 2016
Registry last updated
Aug 26, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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