Immune Response in Lung Cancer

This study is designed to evaluate the importance of the immune cells localization (distribution) between malignant tumor islets and surrounding stroma and to investigate the associations between these immune cells as well as cytokines and clinicopathological and prognostic factors of non-small cell lung cancer (NSCLC) patients.

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Key information

Conditions

Lung Cancer Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Lithuanian University of Health Sciences

Kaunas, LT 44307, Lithuania

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Eastern Cooperative Oncology Group (ECOG) score of 0-1
Patients with histologically documented non-small cell lung cancer
Control group - patients without non-small cell lung cancer
Written (signed) Informed Consent to participate in the study

Exclusion criteria

Any other malignancies within 5 years
Any unstable systemic disease (including active infections, significant cardiovascular disease)
Prior chemotherapy or radiotherapy
Autoimmune disease
Nursing or pregnant women

Treatment and study plan

Primary outcomes

progression-free survival

Time frame: one year after enrolment to the study

Secondary outcomes

overall survival

Time frame: 3 years

Sponsors and collaborators

Lead sponsor

Lithuanian University of Health Sciences

Other

Registry information

Acronym: IRLC

Important dates

Study start: 2012
Primary completion: 2015
Study completion: 2016
First posted: Oct 7, 2013
Registry last updated: Jun 23, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed