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OpenTrials
Completed

NCT Number: NCT00699868

Immune Response and Cytomegalovirus in Intensive Care Unit (ICU) Patients

This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.

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Key information

Conditions

Cytomegalovirus Infection Cytomegalovirus Infections DNA Virus Infections Herpesviridae Infections Infections Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hôpital de Sainte Marguerite- Service de Réanimation Médicale

Marseille, 13009, France

About this study

Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age more than 18-year-old
  • Informed consent

Exclusion criteria

  • minors,
  • pregnant or lactating women,
  • adults under guardianship,
  • immunosuppression at the entrance to resuscitation,
  • AIDS

Treatment and study plan

Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings

Other

Sampling of blood

Primary outcomes

  1. Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV

    Time frame: 24 months

Secondary outcomes

  1. Bring to light the quantitative and qualitative immunological modifications of cells NK in the consequences of an infectious shock

    Time frame: 24 months

Sponsors and collaborators

Lead sponsor

Assistance Publique Hopitaux De Marseille

Other

Registry information

Official study title

Cellular Immunity, Cytomegalovirus Infection and Septic Shock in ICU Patients

Acronym: 2006/25

Important dates

Study start
2008
Primary completion
2011
Study completion
2011
First posted
Jun 18, 2008
Registry last updated
Jun 4, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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