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NCT Number: NCT07725198

Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual Therapy

This study used a prospective, randomized, repeated-measures experimental design to investigate the immediate effects of two upper cervical manual therapy interventions on craniovertebral angle (CVA), clinician-perceived atlas position, and musculoskeletal ultrasound-derived obliquus capitis inferior (OCI) muscle morphology

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Key information

Conditions

Head and Neck Headache Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Florida Gulf Coast University Marieb Hall 101

Fort Myers, Florida, 33965, United States

Location status: Recruiting

Location contact

Rob Sillevis, PhD

CONTACT

[email protected]

239-7454312

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • read and understand English
  • no previous history of cervical spine surgery or traumatic cervical injury
  • no contraindications to cervical manual therapy

Exclusion criteria

  • any absolute contraindications to cervical manipulation
  • any other medical condition considered unsafe for manual therapy.

Treatment and study plan

Thrust long-axis manipulation of C1-C2

Other

One thrust manipulation is provided in the thrust group. a 5 second long axis hold traction of C1-C2 was repeated 3 times in the mobilization group

Primary outcomes

  1. MSK Ultrasound

    Time frame: before intervention, immediately after, and 24 hours after intervention

    MSK Ultrasound measure of the Obliquues Capitis inferior muscle lenght and width

Secondary outcomes

  1. Atlas position

    Time frame: before intervention, immediately after, and 24 hours after intervention

    Atlas position relative to the head measured wth palpation of C1 transverse process

  2. Craniovertebral angle

    Time frame: before intervention, immediately after, and 24 hours after intervention

    Measure of the Craniovertebral angle using photography

Study contacts

Contact information is provided by the study sponsor or research team.

Rob Sillevis, PhD

CONTACT

[email protected]

239-7454312

Sponsors and collaborators

Lead sponsor

Florida Gulf Coast University

Other

Registry information

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Jul 24, 2026
Registry last updated
Jul 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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