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Completed

NCT Number: NCT07465419

IJV Catheterization and Intracranial Pressure Via ONSD

The aim of this study is to evaluate the effect of internal jugular vein catheterization on intracranial pressure in intubated patients in the intensive care unit using optic nerve sheath diameter

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sivas Cumhuriyet University

Sivas, 58140, Turkey (Türkiye)

About this study

Before central venous catheter insertion, the baseline ONSD value will be determined by measuring the optic nerve sheath diameter in the supine and Trendelenburg positions (15 degrees head down).

Immediately after central venous catheter insertion, the measurement will be taken while the patient is still in the Trendelenburg position. The measurement will be repeated at 5, 15, and 30 minutes after the patient is placed in the supine position.

Transorbital optic nerve sheath diameter measurements will be performed using the linear probe of the ultrasound device routinely used in our clinic. The ultrasound linear probe will be gently placed on the eyelid over the closed eye, ensuring no pressure is applied to the patient's eye. The length of the line representing the optic nerve sheath diameter, which intersects the line drawn 3 mm downwards from the lower edge of the eyeball seen on the ultrasound, will be measured and recorded. The optic nerve sheath diameter will be measured transorbitally vertically once from each eye during the first measurement, and the average will be taken.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The study will include adult patients over 18 years of age who are on mechanical ventilation support and monitored in the intensive care unit.

Exclusion criteria

  • patients with intracranial tumors
  • patients with acute traumatic brain injury
  • patients diagnosed with acute or chronic eye diseases
  • hypercarbic patients
  • Patients receiving inotropic support
  • patients using medications that affect intraocular pressure

Treatment and study plan

Internal Jugular Vein Catheterization

Procedure

Internal jugular vein catheterization

Primary outcomes

  1. Optic nerve sheath diameter

    Time frame: Prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

    Optic nerve sheath diameter will be measured via ultrasound prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

Sponsors and collaborators

Lead sponsor

Cumhuriyet University

Other

Registry information

Official study title

Evaluation of the Effect of Internal Jugular Vein Catheterization on Intracranial Pressure Using Optic Nerve Sheath Diameter in Intubated Patients in the Intensive Care Unit

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 11, 2026
Registry last updated
Jun 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.