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Recruiting

NCT Number: NCT06214689

IDH1 and OCT4 in High Grade Astrocytoma

observation of IDH1 and OCT4 markers level and high grade astrocytoma patients prognosis after excision.

Recruiting

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Key information

Conditions

High Grade Astrocytoma Astrocytoma Glioma Neoplasms Neoplasms by Histologic Type Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Nerve Tissue Neoplasms, Neuroepithelial Neuroectodermal Tumors

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

explore the relationship between prognosis and IDH1 and OCT4 biomarkers after high grade astrocytoma excision , according to progression free survival and overall survival , in prospective and retrospective samples.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients of high grade astrocytic glioma patients fit for surgery

Exclusion criteria

  • patients of low grade glioma patients unfit for surgery

Treatment and study plan

biomarkers analysis

Other

IDH1 and OCT4 markers analysis of surgical specimens of high grade astrocytoma

Primary outcomes

  1. IDH1 and OCT4 markers and their relation to postoperative prognosis of high grade astrocytoma patients

    Time frame: baseline

    explore the relationship between prognosis (progression free and overall survival ) and biomarkers (IDH1 and OCT4 ) after excision of high grade astrocytoma

Study contacts

Contact information is provided by the study sponsor or research team.

Abdelrahman A Salama, resident

CONTACT

[email protected]

01002796190

Mahmoud H Ragab, professor

CONTACT

[email protected]

01004001789

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

IDH1 and OCT4 Markers as a Prognostic Factor in Clinical Outcome of High Grade Astrocytic Glioma

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jan 19, 2024
Registry last updated
Aug 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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