Identifying Molecular Drivers of Cancer

The primary aim of this study is to identify drivers of cancer by performing comprehensive genetic, proteomic, and metabolomic characterization of patient samples as a basis for understanding the underlying cause of disease.

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Key information

Conditions

Cancer Advanced Cancer Neoplasms Tumor

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States

About this study

This study involves looking at the DNA, RNA, proteins, and metabolites in blood and tissue samples collected from subjects and linking them to their health information. By doing so, researchers hope to discover the underlying molecular causes of human diseases with the hope that this information can be used for the development of diagnostic tests and more effective treatments.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients diagnoses with cancer but healthy enough to undergo a biopsy procedure
Between the ages of 18 and 100

Exclusion criteria

Patients who are pregnant

Treatment and study plan

Molecular profile

Genetic

Patients and their treating physician will obtain the patient's genetic risk assessment

Other names: Genomic targeting

Primary outcomes

Genetic profiling

Time frame: Up to 15 years

To determine genetic changes associated with the development and growth of human disease. This should lead to better ways to detect, prevent, and treat a wide variety of human health conditions, including cancer.

Sponsors and collaborators

Lead sponsor

Avera McKennan Hospital & University Health Center

Other

Registry information

Important dates

Study start: 2014
Primary completion: 2018
Study completion: 2018
First posted: Jun 12, 2015
Registry last updated: May 25, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed