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NCT Number: NCT06759220

Hystrolaparoscopic Findings in Infertile Women With Previous Uterine Surgery

1. to determine the rate and pattern of abnormal laparoscopic finding among the infertile women with history of previous uterine surgery. 2. To detemine the rate and pattern of abnormal hysteroscopic finding among infertile women with with history of previous uterine sergery 3. to evaluate the value of doing combined laparoscopy and hysteroscopy in infertile women with with history of previous uterine surgery. 4. To determine possible risk factors of pelvic adhesions detected during laparoscopy. 5. To determine possible risk factors causing cs niche.

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Key information

Age range

20 year–35 year

Sex eligibility

Female

Study type

Observational

Primary location

Women's health hospital Assiut University

Asyut, Egypt

About this study

nfertility(1), which refers to the inability of a couple to conceive after one year of regular unprotected sexual intercourse, is the commonest indication for gynacological consultation. primary infertility - where someone who's never conceived a child in the past. secondary infertility(2) - where someone has had 1 or more pregnancies in the past, but is having difficulty conceiving again.there are many causes for infertility. (3)uterine causes as uterine fibroids or malformations.tubal factors as tuboperitoneal adhesions,unilateral or bilateral proximal occlusion unilateral or bilateral hydrosalpinx or pyosalpinx.Ovarian factors ovarian cyst,polycystic ovaries.pelvic causes as adhesions ,endometriosis and miscellaneous. laparoscopy can be used as the gold standard diagnostic tool which allows direct visualization of all pelvic organs. It also helps in detailed assessment of fallopian tubes. The advantage behind using laparoscopy is that the treatment of certain conditions such as tubal obstruction, endometriosis, and pelvic adhesions can be done at the same time during diagnosis. If needed, laparoscopic chromopertubation can also be done for tubal patency during the same sitting. (4)Hysteroscopy is the direct visualization of the uterine cavity using an endoscope. Uterine cavity evaluation is very much needed to do achieve total infertility workup. Uterine abnormalities are present among 10-15% of couples who seek treatment of infertility. For evaluation of endometrial factors,(5) hysteroscopy considered to be a gold standard. Diagnostic h hysteroscopy can detect uterine anomalies which remain undetected in USG and other routine investigations.

Many studies reported the occurrence of pelvic adhesions following cesarean section with its related consequences.

pelvic adhesions may affect both reproductive system anatomy and function, causing various associated conditions. Pelvic adhesions may cause secondary infertility, which might be due to dyspareunia, disturbing tubo-ovarian relationship, or disturbing peristaltic movement of fallopian tube.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All women between20 to 35 yrs old with secondary infertiliy for 2 years
  • Women with previous uterine surgery

Exclusion criteria

  • Female with major medical illness(Uncontrolled daibetes, cardiac diseases, uncontrolled thyroid disorders)
  • Abnormal semen parameter of the husband.

Treatment and study plan

Primary outcomes

  1. Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery

    Time frame: Baseline

    Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery

Study contacts

Contact information is provided by the study sponsor or research team.

Dalia Ali, Master

CONTACT

[email protected]

01065206186

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Hystrolaparosciopic Findings in Infertile Women With Secondary Infertility

Important dates

Study start
2025
Primary completion
2027
Study completion
2028
First posted
Jan 6, 2025
Registry last updated
Jan 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.