Skip to main content
OpenTrials
Completed

NCT Number: NCT04829578

Hypnosis for Chronic Idiopathic Pruritus

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, for which there is no specific treatment. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Chronic Idiopathic Pruritus

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chu de Nice

Nice, France, 06000

About this study

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, with significative impact on quality of life. At present, there is no specific treatment for CIP. Topical steroids are frequently used, with partial efficacy, and adverse effects. Hypnosis is a specific state of conscience. It differs from waking state, sleeping state, relaxation, or meditation. In this state, the person is highly responsive to suggestion. In medicine, hypnosis can be used to engage the internal resources of the person against unpleasant feelings. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female of at least 18 years at screening
  • Diagnosis of chronic (at least 6 wks.) idiopathic pruritus
  • Pruritus Numeric Rating Scale > = 4

Exclusion criteria

  • Pruritus caused by a dermatological or a systemic conditions
  • Suicidal crisis, moderate, or severe
  • Psychosis (schizophrenia, persistent delusional disorder)
  • Bipolar disorder, not stabilized or decompensating
  • Personality disorder, decompensated

Treatment and study plan

Hypnosis

Other

Chronic idiopathic pruritus is treated by hypnosis

Primary outcomes

  1. Change From Baseline in Pruritus Numeric Rating Scale

    Time frame: Day 84

    Assessment of the intensity of pruritis in Pruritus Numeric Rating Scal; the minimum and maximum values 0 to 10

Secondary outcomes

  1. Change From Baseline in Pruritus Verbal Rating Scale

    Time frame: Day 84

    Assessment of Pruritus by pruritus Verbal Rating Scale; the minimum and maximum values 0 to 4

  2. Change From Baseline in Sleeping Scale

    Time frame: Day 84

    assessment in sleeping scale ; the minimum and maximum values 0 to 10

  3. Change From Baseline in DLQI scale

    Time frame: Day 84

    assessment in DLQI scale; result between 0 to 30

  4. Change From Baseline in HAD scale

    Time frame: Day 84

    assessment in HAD scale; result between 0 to 42

  5. Change From Baseline in usage of topical steroids

    Time frame: Day 84

    assessment in usage of topical steroids

  6. Evaluation of tolerance of hypnosis

    Time frame: Day 84

    assessment of tolerance of hypnosis with report of adverse event

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

A Prospective Study of Hypnosis for Chronic Idiopathic Pruritus

Important dates

Study start
2021
Primary completion
2021
Study completion
2022
First posted
Apr 2, 2021
Registry last updated
Mar 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.