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NCT Number: NCT05942885

Hypnosis: a Path to Appeasement

Hypnosis is a technique allowing the patient to focus his mental attention on a thought or a sensation, with the aim of reducing or modulating the intensity of a negative feeling or an ordeal encountered during the course of treatment. This tool can be used when patients are faced with chronic disorders (pain, anxiety, ...) or iatrogenic effects (nausea, asthenia, ...).

The patient is referred to hypnosis care by the doctor, psychologist or paramedics who follow him, when they detect a need.

Several scientific studies have shown the effectiveness of hypnosis in improving the quality of life of patients with breast cancer and in reducing pain during invasive procedures. On the other hand, in hematology, no research has measured the evolution of anxiety, over time, in patients receiving hypnotherapy.

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Key information

Conditions

Hematologic Cancer Anxiety Disorders Hematologic Diseases Hematologic Neoplasms Hemic and Lymphatic Diseases Immune System Diseases Immunoproliferative Disorders Lymphatic Diseases Lymphoma Lymphoma, B-Cell Lymphoma, Follicular Lymphoma, Large B-Cell, Diffuse Lymphoma, Non-Hodgkin Lymphoproliferative Disorders Mental Disorders Neoplasms Neoplasms by Histologic Type Neoplasms by Site

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Service MB1 - Hôpital Lyon Sud - HCL

Lyon, Pierre-Bénite, 69495, France

Location status: Recruiting

Location contact

Thomas Bert

CONTACT

[email protected]

04.78.86.43.45

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over 18 years old, fluent in French.
  • Patients starting hypnotherapy for anxiety disorders.
  • Anxiety score on the HADS scale (Hospital Anxiety and Depression Scale) greater than or equal to 8/21
  • Patients with diffuse large cell B-cell lymphoma or follicular lymphoma, whatever the stage of the disease.
  • Diagnosis announcement less than 2 months old

Exclusion criteria

  • Persons deprived of their liberty by a judicial or administrative decision
  • Adults subject to a legal protection measure

Treatment and study plan

anxiety questionnaire

Other

Patient undergoing hypnosis session will have their anxiety measured just before the third session of hypnosis and after during a telephonic consultation. The result will be compared to the anxiety level before the first hypnosis session

Primary outcomes

  1. Evolution of anxiety

    Time frame: Week 6 after 2 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

Secondary outcomes

  1. Evolution of anxiety before hypnotherapy and after 3 months of follow-up in hypnotherapy

    Time frame: Month 3 after 3 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

  2. Evolution of anxiety between D0 and M3 according to the type of lymphoma

    Time frame: Month 3 after 3 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions for two subgroups : follicular lymphoma and diffuse large b-cell lymphoma. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

  3. Evolution of anxiety between D0 and W6 according to the type of lymphoma

    Time frame: Week 6 after 2 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions for two subgroups : follicular lymphoma and diffuse large b-cell lymphoma. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

  4. Evolution of anxiety between D0 and W6 according to the gender of the patient

    Time frame: Week 6 after 2 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions for two subgroups : man and woman. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

  5. Evolution of anxiety between D0 and M3 according to the gender of the patient

    Time frame: Month 3 after 3 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions for two subgroups : man and woman. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

  6. Evolution of anxiety between D0 and W6 according to age category

    Time frame: Week 6 after 2 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions for two subgroups : under 60 years old ans over 60 years old. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

  7. Evolution of anxiety between D0 and M3 according to age category

    Time frame: Month 3 after 3 hypnosis sessions

    Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions for two subgroups : under 60 years old ans over 60 years old. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious.

Study contacts

Contact information is provided by the study sponsor or research team.

Thomas BERT

CONTACT

[email protected]

04.78.86.43.45

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Acronym: HYCVA

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Jul 12, 2023
Registry last updated
Sep 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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