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NCT Number: NCT06635603

HYPERTENSIVE CRISIS AND ATMOSPHERIC PRESSURE RELATIONSHIP

relationship between the onset times of symptoms and the regions of patients presenting to the emergency department with hypertensive crisis (systolic ≥180 and/or diastolic ≥110 mmHg) and the fluctuations in atmospheric pressure

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Etlik City Hospital

Ankara, 06170, Turkey (Türkiye)

Location status: Recruiting

Location contact

Bedriye Muge SONMEZ, ass. prof.

SUB_INVESTIGATOR

Elif HAMZACEBIOGLU KAYISOGLU, Specialist

CONTACT

[email protected]

+905453300679

Elif HAMZACEBIOGLU KAYISOGLU, Specialist

PRINCIPAL_INVESTIGATOR

Fatma BUYUKCELEN CIFTCI, resident

SUB_INVESTIGATOR

Fatma Nur KOC, Resident

SUB_INVESTIGATOR

Gulsen AKCAY, Ass. Prof.

PRINCIPAL_INVESTIGATOR

Gulsen AKCAY, Associate Professor

CONTACT

[email protected]

+905052874949

Murat Ozdemir, Specialist

SUB_INVESTIGATOR

About this study

Hypertensive emergency is defined as grade 3 hypertension (systolic ≥180 and/or diastolic ≥110 mmHg) that causes end-organ damage, requiring urgent intervention and intensive care admission . Hypertensive crisis is described as severe hypertension not associated with end-organ damage. Some sources define hypertensive crisis as hypertension of grade 3 or higher, while others refer to it as severe hypertension without specifying a threshold .

Literature reviews, published guidelines, and studies indicate that the definitions and treatment approaches for hypertensive crisis differ between Europe and America, with variations in management from one physician to another . Seasonal blood pressure fluctuations are influenced by external temperature, indoor temperature, humidity, atmospheric pressure, and wind . Notably, during periods of low atmospheric pressure, blood pressure measurements show statistically significant increases compared to other days . Consequently, the frequency of life-threatening conditions associated with hypertension, such as intracranial hemorrhage and abdominal aortic aneurysm rupture, has been observed to increase on days when atmospheric pressure changes .

In our study, we aim to investigate the relationship between the onset times of symptoms and the regions of patients presenting to the emergency department with hypertensive crisis (systolic ≥180 and/or diastolic ≥110 mmHg) and the fluctuations in atmospheric pressure

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 and above
  • Hypertensive crisis (systolic ≥180 and/or diastolic ≥110 mmHg)

Exclusion criteria

  • Patients presenting with hypertensive emergency (those with end-organ damage)
  • Patients who have traveled to another city or district within the last 4 days
  • Pregnant patients

Treatment and study plan

Primary outcomes

  1. Hypertensive Crisis

    Time frame: from enrollment to the end of follow up duration of 7 days

    Patients' blood pressure values evaluation in terms of atmospheric pressure and weather conditions

Study contacts

Contact information is provided by the study sponsor or research team.

Elif HAMZACEBIOGLU KAYISOGLU, Specialist

CONTACT

[email protected]

+905453300679

Gulsen AKCAY, Ass. Prof.

CONTACT

[email protected]

+905052874949

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi

Other

Collaborators

  • Etimesgut Military Hospital

Registry information

Official study title

HYPERTENSIVE CRISIS AND ATMOSPHERIC PRESSURE RELATIONSHIP: A PROSPECTIVE STUDY

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Oct 10, 2024
Registry last updated
Oct 10, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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