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Completed

NCT Number: NCT07249541

Hypermobility, Foot Posture, and Scoliosis Severity

Adolescent Idiopathic Scoliosis is a three-dimensional spinal deformity that may also affect joint mobility, lower limb alignment, and overall posture. Joint hypermobility and foot posture abnormalities, including pronation or supination, are commonly observed in adolescents and may contribute to postural imbalance or altered biomechanical loading. However, the relationship between hypermobility, foot posture, and the severity of scoliosis remains unclear.

The aim of this study is to examine whether generalized joint hypermobility and foot posture characteristics are associated with Cobb angle severity in adolescents diagnosed with Adolescent Idiopathic Scoliosis. Hypermobility will be assessed using the Beighton Score, and foot posture will be evaluated with the Foot Posture Index. Understanding these associations may help clinicians better evaluate biomechanical factors related to scoliosis and guide future preventive or therapeutic approaches.

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Key information

Conditions

Joint Hypermobility Adolescent Idiopathic Scoliosis Foot Posture Joint Diseases Joint Instability Musculoskeletal Diseases

Age range

10 year–19 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istinye University

Istanbul, 34010, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Adolescent Idiopathic Scoliosis
  • Age 10-19 years
  • Cobb angle ≥ 10° on standing Anterior-Posterior radiograph
  • Ability to participate in physical assessments
  • Voluntary consent to participate

Exclusion criteria

  • Neuromuscular, syndromic, or congenital scoliosis
  • Previous spinal surgery
  • Lower extremity orthopedic conditions affecting foot posture
  • Neurological or rheumatological disorders affecting joint mobility
  • Communication or cognitive difficulties limiting participate

Treatment and study plan

Assessment

Other

Participants diagnosed with Adolescent Idiopathic Scoliosis will undergo assessments of hypermobility (Beighton Score), foot posture (Foot Posture Index), and scoliosis severity (Cobb angle).

Primary outcomes

  1. Foot Posture Index-6

    Time frame: 4 weeks

    The Foot Posture Index-6 is a reliable and valid clinical assessment tool used to objectively evaluate foot posture in the pronation-supination spectrum. The assessment is performed with the individual in a relaxed standing position and is based on six observational criteria. The total score ranges from -12 to +12, where higher scores indicate a more pronated foot posture, while lower scores reflect a more supinated posture. A score close to 0 represents a neutral foot posture.

  2. The Beighton Test

    Time frame: 4 weeks

    This is a standardized and easily applicable clinical assessment method used to determine joint hypermobility. The total score for the nine-item test ranges from 0 to 9. A total score of ≥4 indicates the presence of hypermobility. It is scored out of 9 points; each positive finding is evaluated as 1 point.

Secondary outcomes

  1. Feiss Line Test

    Time frame: 4 weeks

    Used to evaluate the structural characteristics of the arch of the foot. In this test, the position of the navicular tubercle above or below a line drawn by aligning the medial malleolus, navicular tubercle, and first metatarsal head indicates the presence of pes planus or pes cavus.

  2. Sit-Reach Test

    Time frame: 4 weeks

    This is a common field test that evaluates the flexibility of the hamstring and lumbar muscles. The participant sits in a straight position, knees straight, and the soles of their feet touching the test box, reaching forward; the distance between their toes indicates the level of flexibility.

Sponsors and collaborators

Lead sponsor

Istinye University

Other

Registry information

Official study title

Investigation of the Relationship Between Hypermobility, Foot Posture, and Scoliosis Severity in Adolescents With Idiopathic Scoliosis

Acronym: AIS

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 25, 2025
Registry last updated
Jun 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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