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Completed

NCT Number: NCT01974739

Hydrochloorthiazide and Hypernatriaemie

Acquired hypernatremia appears to be associated with mortallity in ICU. To reduce hypernatremia and shorten the time of hypernatremia, we investigate the effect of hydrochloorthiazide compared to a placebo

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Key information

Conditions

Hypernatraemia Hypernatremia Metabolic Diseases Nutritional and Metabolic Diseases Water-Electrolyte Imbalance

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Medical Centre Leeuwarden

Leeuwarden, Provincie Friesland, 8801 AD, Netherlands

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • sodium > 142

Exclusion criteria

  • no informed consent

Treatment and study plan

Hydrochloorthiazide

Drug

Placebo

Drug

Primary outcomes

  1. sodium level

    Time frame: 7 days

    a decrease of 5 mmol/L sodium in plama

Secondary outcomes

  1. time hypernatraemia

    Time frame: 7 days

    decrease of duration high sodium level in plasma

Sponsors and collaborators

Lead sponsor

Frisius Medisch Centrum

Other

Registry information

Official study title

Hypernatraemia and Diuretics in Intensive Care Patients

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Nov 4, 2013
Registry last updated
Jun 23, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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