Hürthle Cell Carcinoma and Follicular Thyroid Carcinoma

The goal of this retrospective study is to evaluate in patients with HCC and FTC who underwent lobectomy. The main questions it aims to answer are:

* The necessity of completion thyroidectomy based on the clinicopathological characteristics * Prognosis Participants underwent thyroid lobectomy Researchers compared HCC and FTC groups to see the prognosis after lobectomy.

Completed

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Key information

Conditions

Huerthle Cell Carcinoma Adenocarcinoma Carcinoma Neoplasms Neoplasms by Histologic Type Neoplasms, Glandular and Epithelial

Sex eligibility

All sexes

Study type

Observational

About this study

Background The prognosis of Hürthle cell carcinoma (HCC) and follicular thyroid carcinoma (FTC) is poorly understood. These types of cancers are usually confirmed after diagnostic lobectomy. We aimed to evaluate the clinicopathological characteristics and prognoses of patients with HCC and FTC who did not undergo completion thyroidectomy.

Materials and Methods We screened 221 patients diagnosed with FTC or HCC after thyroid lobectomy at Yonsei Severance Hospital between January 2000 and December 2020. After excluding patients who underwent complete thyroidectomy, 184 patients with FTC and 37 patients with HCC were included.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Follicular thyroid carcinoma
Hurthle cell carcinoma
Lobectomy

Exclusion criteria

Completion thyroidectomy
Total thyroidectomy

Treatment and study plan

Primary outcomes

Disease-free survival (DFS)

Time frame: From January 2000 to March 2023

a comparison of disease-free survival (DFS) between FTC and HCC groups

Secondary outcomes

TNM stage

Time frame: From January 2000 to March 2023

a comparison of TNM stage between FTC and HCC groups

Sponsors and collaborators

Lead sponsor

The Catholic University of Korea

Other

Registry information

Official study title

Clinicopathological Characteristics of Hürthle Cell Carcinoma and Follicular Thyroid Carcinoma Without Completion Thyroidectomy

Acronym: HCC and FTC

Important dates

Study start: 2000
Primary completion: 2020
Study completion: 2023
First posted: Aug 1, 2023
Registry last updated: Aug 1, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed