Human Papilloma Virus In Male Infertility

WHO defines infertility as the inability to conceive after at least 12 months of regular, unprotected sexual intercourse.

Reduced male fertility can be the result of congenital and acquired urogenital abnormalities, infections of the male accessory glands, increased scrotal temperature (varicocele), endocrine disturbances, genetic abnormalities and immunological factors ,

In 40-60% of cases the only abnormality is the semen analysis and there is no relevant history or abnormality on physical examination and endocrine laboratory testing (idiopathic male infertility).

Semen analysis reveals a decreased number of spermatozoa (oligozoospermia), decreased motility (asthenozoospermia) and many abnormal forms on morphological examination (teratozoospermia). Usually, these abnormalities come together and are described as the OAT-syndrome (oligo-astheno-teratozoospermia).

Human papillomavirus (HPV) is one of the most common sexually transmitted viruses, and males and females from different regions are generally susceptible.

More than 120 HPV genotypes are known to distribute in the skin and mucous membranes, including the pubic area, oral cavity and perianal region, and can be transmitted through skin contact or any other surface contact related to the genital area.

Inclusion criteria

• Patients with at least 1 year of unprotected sexual intercourse without conception.
• Patients with genital warts

Exclusion criteria

• Hypergonadotropic/hypogonadotropic hypogonadism
• Azoospermia
• chromosome abnormalities
• undescended testis
• mumps orchitis