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OpenTrials
Completed

NCT Number: NCT04490668

Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery

We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

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Key information

Conditions

Gastric Cancer Anastomotic Leak Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Neoplasms Neoplasms by Site Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Stomach Diseases Stomach Neoplasms

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

About this study

Anastomotic leakage after gastric cancer surgery is not very common but it is a very critical postoperative complication. Anastomotic leakage severely compromises the recovery after surgery. It increases the overall burden of patients and hospital resources. Postoperative mortality is higher in patients with anastomotic leakage.

Human albumin is routinely administered after surgery with a unproven hypothesis that the human albumin is beneficial to prevent anastomotic leakage. We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Histologically confirmed gastric cancer
  • Patients who underwent radical gastrectomy

Exclusion criteria

  • Patient who did not undergo gastrectomy

Treatment and study plan

Human Albumin

Biological

Patients received intravenous human albumin after gastric cancer surgery. Overall quantity of human albumin were recorded.

Primary outcomes

  1. Comparison of the rate of anastomotic leakage

    Time frame: Up to one months after the discharge of last patient

    The rate of anastomotic leakage were compared among both groups

Sponsors and collaborators

Lead sponsor

Ruijin Hospital

Other

Registry information

Official study title

Association of Human Albumin With Anastomotic Leakage After Gastric Cancer Surgery

Important dates

Study start
2016
Primary completion
2018
Study completion
2019
First posted
Jul 29, 2020
Registry last updated
Jul 29, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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