Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06731309

HS ABSCESSES: I&D VS PUNCH DEBRIDEMENT

This randomized-control trial is designed to determine the recurrence rate of HS abscesses following drainage via two methods: I&D with a linear incision and PD with an 8mm punch biopsy. In this context, recurrence is a newly described HS abscess adjacent to or within the previously operated area, for which a second intervention is deemed necessary. We hypothesize that PD may yield a more favorable recurrence rate. In addition to comparing recurrence rates, this randomized-control trial will also evaluate postprocedural pain, the occurrence and type of complications, and patients' quality of life associated with both procedures. These additional factors are crucial in assessing the overall effectiveness and patient satisfaction associated with each method, further informing the potential establishment of PD as the new gold standard for draining small, painful, acute HS abscesses.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Hidradenitis Suppurativa (Acne Inversa) Abscess Bacterial Infections Bacterial Infections and Mycoses Hidradenitis Hidradenitis Suppurativa Infections Inflammation Pathologic Processes Pathological Conditions, Signs and Symptoms Skin Diseases Skin Diseases, Bacterial Skin Diseases, Infectious Skin and Connective Tissue Diseases Suppuration Sweat Gland Diseases

Age range

16 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Erasmus MC

Rotterdam, South Holland, Netherlands

Location contact

Hessel H van der Zee

CONTACT

+31 10 704 0110

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with HS
  • Has an abscess requiring drainage with a maximum diameter of 5 centimeters.
  • Age 16 years or older
  • Willing and able to provide informed consent

Exclusion criteria

  • Has other conditions that could interfere with the study, as estimated by physician
  • Unable to comply with follow-up visits
  • Allergic to lidocaine and/or adrenaline.

Treatment and study plan

Punch Debridement

Procedure

A punch biopsy tool is positioned over the inflamed follicular unit, and a small circle of skin (4 to 8 mm in diameter) is excised. A firm twisting motion is necessary to ensure adequately deep excision.

Incision and Drainage

Procedure

Incision and Drainage is a minimally invasive surgical procedure often employed for the treatment of intensely painful, tense, and fluctuant abscesses that are too deep to drain spontaneously. After administration of a broad circumferential local anesthetic, a small linear incision is made using a standard scalpel blade. Digital pressure is applied to expel the fluid collection. Saline rinses can be used to flush out the remaining contents. This method offers instant pain relief, commonly performed in acute settings by dermatologists, emergency department physicians and general practitioners

Primary outcomes

  1. Recurrence

    Time frame: 1 month

    Recurrence rate in percentage of abscesses recurring after drainage

Study contacts

Contact information is provided by the study sponsor or research team.

Hessel H van der Zee, MD, PhD

CONTACT

[email protected]

+31 10 704 0110

Sponsors and collaborators

Lead sponsor

Erasmus Medical Center

Other

Registry information

Official study title

ABSCESS DRAINAGE in HIDRADENITIS SUPPURATIVA: INCISION and DRAINAGE VERSUS PUNCH DEBRIDEMENT

Acronym: HSPUNCH

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Dec 12, 2024
Registry last updated
Dec 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.