serum sodium measurment
Otherserum sodium measurment
NCT Number: NCT06962124
We aimed to determine the effect of accurate assessment of dry weight based on measuring blood sodium level before dialysis to evaluate the effect of adjustment of ultrafiltration rate on hemodialysis complications and take a step forward to improve patient care and the quality of hemodialysis.
Trial opening soon.
Get Notified18 year–65 year
All sexes
Interventional
Not applicable
Dialysis has become an integral part of daily routine for kidney failure patients. so, if we can reduce complications during sessions, we will reduce the burden of life as a whole ¬. Haemodialysis problems are frequent (1).
The definitions of dry weight have changed over time but can be defined as the lowest post-dialysis weight tolerated without significant signs of hypovolaemia.(2) It should be mentioned that the incidence of complications during hemodialysate depends on the balance between the rate of ultrafiltration and changes in plasma volume. The amount of ultrafiltration is typically determined by calculating the patient's dry weight.(3) Common problems during haemodialysis, in order of frequency, are: hypotension of around 23%, muscle cramps of roughly 10 to 20%, and nausea and vomiting of 10%. (4, 5). About 60 to 90% of dialysis patients suffer fatigue, which is one of the most prevalent complaints in people receiving hemodialysis.(6) aggressive ultrafiltration and targeting an inappropriately low dry weight can lead to intradialytic hypotension (IDH), nausea, central nervous system dysfunction, cramping, and risks compromising vascular access and worsening residual renal function.(7) Determining the patients' accurate dry weight is essential to minimizing these issues. When dry weight is accurately determined, quick variations in blood volume are avoided, which lowers the risk of problems during haemodialysis(8). The measurement of arterial natriuretic peptide (half-life of approximately 2 to 4 minutes), cyclic guanidine monophosphate, the diameter of the inferior vena cava (by echocardiography), bioimpedance (based on resistance measurement), and blood volume (by tracking changes in serum protein and hemoglobin) are used to determine dry weight.(9, 10) These techniques frequently need specialized equipment and are expensive. However, one practical way to measure dry weight prior to dialysis is to measure the amount of sodium, the most prevalent cation in extracellular fluid .(11)
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
1- Impaired consciousness 2- participant's withdrawal from the study 5-death 3- severe blood supply problem in the fistula or vascular access 4-migration or travel during the study
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serum sodium measurment
Time frame: 3 month ( 39 session for each patient , 13 session per month)
We aimed to determine the effect of assessment of dry weight based on measuring blood sodium level before dialysis to evaluate the effect of adjustment of ultrafilteration rate on haemodialysis complications and take a step forward to improve patient care and the quality of hemodialysis
Assiut University
Other
The Effect of Accurate Measurement of Dry Weight Based on pre_dialysis Serum Sodium Measurement on Reduction of Hemodialysis Complications
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