How to Predict Post-Surgical Bleeding and Hemoglobin in Liposuction?

To evaluate the effect of using a mathematical model developed through pre- and post-surgical hemoglobins to predict the volume to aspirate in patients undergoing primary body liposuction.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Bleeding Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms Surgery

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

National Western Speciality Hospital, Mexican Social Security Institute, Guadalajara, Jalisco, Mexico

About this study

Postoperative anemia is a significant risk associated with liposuction, yet the scientific literature lacks detailed data on blood loss relative to the volume of fat removed. To address this, the investigators aimed to develop a mathematical formula predicting the decrease in postoperative hemoglobin (Hb post) based on preoperative hemoglobin (Hb pre), Body Mass Index (BMI), and the volume of fat suctioned. An observational, analytical, non-experimental, prospective study was conducted on liposuction patients to validate this predictive formula. Statistical analysis using Spearman's test showed that the results were statistically significant (P < 0.05).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients of indistinct gender, operated on at the Centro Médico Nacional de Occidente for primary liposuction.
Age between 18 to 60 years old
Liposuction technique used: Super wet or Tumescent.
Surgical procedure on any area of the body
Large volume liposuction (> 5 L)
Use of regional anesthesia

Exclusion criteria

Presence of any of the following comorbidities: Systemic Arterial Hypertension or Diabetes Mellitus type 2.
Performance of 2 or more procedures
Use of medications (NSAIDs and/or coadjuvants that modify coagulation times).

Treatment and study plan

Liposuction

Procedure

Primary or secondary liposuction is performed by the surgical staff. The study analyzed variables including weight, height, BMI, preoperative hemoglobin, and aspirated volume. Additionally, preoperative hemoglobin (Hb), hematocrit (Hto), platelets, prothrombin time (Tp), partial prothrombin time (TpT), and International Normalized Ratio (INR) were evaluated. Hb and Hto levels were reassessed 24 hours post-surgery to monitor changes.

Primary outcomes

Bleeding Predicting Method

Time frame: 12 months

Mathematical model based on pre-and post-surgical hemoglobins to further predict estimated bleeding

Sponsors and collaborators

Lead sponsor

Instituto Mexicano del Seguro Social

Other Gov

Registry information

Official study title

Effect of Using a Mathematical Model Based on pre-and Post-surgical Hemoglobin Differences to Determine the Volume to Aspirate in Primary Body Liposuction.

Important dates

Study start: 2022
Primary completion: 2022
Study completion: 2022
First posted: Jun 12, 2024
Registry last updated: Jun 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed