How to Improve Diagnosis in Infective Endocarditis

The purpose is to exam prospective if simple clinical information in combination with a normal s-procalcitonin are sufficient for exclusion of infective endocarditis (IE).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Endocarditis, Bacterial Bacterial Infections Bacterial Infections and Mycoses Cardiovascular Diseases Cardiovascular Infections Endocarditis Heart Diseases Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Cardiology, Aarhus University Hospital

Aarhus, 8200, Denmark

About this study

Despite progress in surgical and medical treatment, infective endocarditis is still associated with high morbidity and mortality.

The variable clinical presentation of IE makes the diagnosis a clinical challenge.

Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections.

The purpose of this study is:

to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected.
to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients > or = 18 year with suspected or verified Infective Endocarditis
By word of mouth or in writing consent

Exclusion criteria

Incapacity

Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Registry information

Official study title

Ph. D Student, Jane Byriel Knudsen, Aarhus University

Important dates

Study start: 2007
Study completion: 2009
First posted: Sep 3, 2007
Registry last updated: Jan 20, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed