Florida State University
Tallahassee, Florida, 32306, United States
NCT Number: NCT06866743
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group. While heat stress can reduce kidney function, previous research has not accounted for physical activity, diet, hydration, or sun exposure.
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Notify Me55 year and older
Female
Observational
Tallahassee, Florida, 32306, United States
Intense heat stress on the body can reduce kidney function. A recent study reported that blood markers of kidney function are lower among people in hotter climates. However, these data did not consider physical activity, food intake, fluid intake, time spent outdoors, or exposure to sunlight. Therefore, the investigators invite participants to help determine whether there are seasonal changes in kidney function biomarkers. This will also help the investigators understand if physical activity, food intake, fluid intake, time spent outdoors, or exposure to sunlight affect kidney function biomarkers between seasons. The investigators are studying female adults post-menopause since they are an understudied group.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
This research focuses on examining seasonal variations in kidney function among postmenopausal females. As an observational study, our approach is non-interventional.
Time frame: Visit 1 (0 months) and Visit 2 (7 months)
Changes in NGAL will be measured in blood samples using enzyme-linked immunosorbent assay.
Time frame: Visit 1 (0 months) and Visit 2 (7 months)
Changes in NGAL will be measured in urine samples using radioimmunoassay.
Time frame: Visit 1 (0 months) and Visit 2 (7 months)
The product of Insulin-like growth factor-binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinase-2 (TIMP-2) will be measured in blood samples using enzyme-linked immunosorbent assays.
Time frame: Visit 1 (0 months) and Visit 2 (7 months)
eGFR will be calculated from creatinine using CKD-EPI equation.
Florida State University
Other
Seasonal Changes in Kidney Function Among Female Adults Post-Menopause
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