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OpenTrials
Completed

NCT Number: NCT01516021

How Fat Influences the Brain

The aim of the current study was to investigate the effect of a high versus a low fat meal (operationalized by high and low fat yoghurt) on homeostatic and gustatory brain regions.

Completed

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Key information

Conditions

Fat Processing in the Brain

Age range

25 year–32 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University Clinic of Tuebingen, MEG Center

Tübingen, 72076, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male
  • healthy

Exclusion criteria

  • lactose intolerance
  • fMRI contraindications (metal implants,...)

Treatment and study plan

intake of high or low fat yoghurt

Dietary Supplement

intake of 500 ml of a high fat yoghurt on one day and intake of 500 ml of a low fat yoghurt on the other day

Primary outcomes

  1. Changes in Cerebral Blood Flow due to the high or low fat yoghurt intake after 30 minutes and 120 minutes compared to a baseline measurement 30 minutes before yoghurt intake.

    Time frame: 30 minutes before as well as 30 minutes and 120 minutes after fat intake

    We were interested in differential brain activations due to the high or low fat meal. To assess this, the mentioned time points are suitable.

    The Cerebral Blood Flow is measured using Arterial Spin Labeling sequences in a functional magnetic resonance tomography.

Sponsors and collaborators

Lead sponsor

University Hospital Tuebingen

Other

Collaborators

  • German Center for Diabetes Research
  • German Federation of Industrial Research Associations
  • German Research Foundation
  • University of Hohenheim
  • Zentrum für Ernährungsmedizin und Prävention

Registry information

Official study title

Fat Intake Modulates Cerebral Blood Flow in Homeostatic and Gustatory Brain Areas in Humans

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Jan 24, 2012
Registry last updated
Jan 24, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.