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OpenTrials
Completed

NCT Number: NCT02985606

How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance

Investigate how manipulating the time between caffeine ingestion and exercise may alter exercise performance and cognition

Completed

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Key information

Conditions

Healthy

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sport and Health Sciences

Exeter, Devon, EX1 2LU, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • vo2max > 55 ml/kg/min
  • females on contraceptive pill

Exclusion criteria

  • recent skeletal muscle injury
  • cardiovascular injury
  • metabolic disease

Treatment and study plan

Caffeine powder -60

Other

Caffeine powder -30

Other

Caffeine powder 0

Other

Placebo powder -60

Other

Placebo powder -30

Other

Placebo powder 0

Other

Primary outcomes

  1. Work done in kilojoules (kJ) during a 15 minute time trial on a cycle ergometer

    Time frame: 15 minutes

Secondary outcomes

  1. Whole body fuel substrate utilisation measured using indirect calorimetry

    Time frame: 10 minutes

  2. Change in plasma caffeine concentration and metabolites

    Time frame: 2 hours 45 minutes

  3. Change in cognitive function measured using stroop test

    Time frame: 2 hours 45 minutes

  4. Collection of saliva for genotyping of CYP1A2

    Time frame: 30 mintes

Sponsors and collaborators

Lead sponsor

University of Exeter

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2018
First posted
Dec 7, 2016
Registry last updated
Oct 16, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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