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OpenTrials
Completed

NCT Number: NCT02394574

Household Air Pollution and Pregnancy Outcome

Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.

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Key information

Conditions

Pregnancy

Age range

Up to 35 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

College of Medicine. University of lbadan, Ibadan

Ibadan, Nigeria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant women who present to the hospital
  • Who cook exclusively with either kerosene or firewood
  • Before the fourteenth week of pregnancy as determined by ultrasound imaging

Exclusion criteria

  • Smoking women or women with smoking family members
  • Women with a high-risk pregnancy defined as:
  • Women with uncontrolled hypertension
  • Women greater than 35 years old carrying their first child
  • Women having triplets or more
  • Women who have had a previous C-section
  • Women carrying babies with fetal abnormalities or as determined by the obstetrician.

Treatment and study plan

Clean Cookstove

Other

Ethanol

Traditional Cookstove

Other

Firewood / Kerosene

Primary outcomes

  1. Adverse Pregnancy Outcomes

    Time frame: At birth

    (first trimester miscarriages, intrauterine growth retardation, low birth weight (300gm less weight in controls relative to intervention group, premature deliveries (deliveries before 37 weeks of pregnancy) and still births.

Secondary outcomes

  1. Reduction in personal exposure to PM2.5, CO and PAH

    Time frame: At birth

    Reduction in personal exposure to PM2.5, CO and PAH in the Ethanol intervention group relative to the control (kerosene/firewood) group

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Registry information

Acronym: HAP

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Mar 20, 2015
Registry last updated
Oct 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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