Skip to main content
OpenTrials
Completed

NCT Number: NCT07510022

Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients

This work aimed to assess the effect of regional climatic differences on postoperative bleeding in Egyptian patients undergoing cardiac surgery with cardiopulmonary bypass, by comparing outcomes between patients from hot climate zones (Upper Egypt) and those from moderate climate zones (Lower Egypt).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hot Climate Bleeding Tendency Cardiac Surgery Cardiovascular Diseases Egyptian Patients Hematologic Diseases Hemic and Lymphatic Diseases Hemorrhagic Disorders Hemostatic Disorders Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Al-Azhar University

Cairo, 11651, Egypt

About this study

Egypt experiences extremely high ambient temperatures, especially during the summer months, with daily highs frequently exceeding 40°C. Such climatic extremes can influence physiological homeostasis in surgical patients by altering fluid balance, cardiovascular strain, and hemostatic function.

Seasonal and climatic variations have been linked to changes in cardiovascular surgical outcomes, including mortality, length of stay, and complication rates. Several large observational studies have noted increased bleeding or transfusion requirements in surgeries performed under certain environmental conditions, though findings remain inconsistent.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years.
  • Both sexes.
  • Egyptian nationality.
  • Underwent open-heart surgery with cardiopulmonary bypass.
  • Complete medical records and postoperative bleeding data are available.

Exclusion criteria

  • Emergency surgeries
  • Pre-existing coagulopathy
  • Use of anticoagulants not discontinued prior to surgery
  • Re-do surgeries

Treatment and study plan

Open Heart Surgery

Procedure

Patients who underwent open heart surgery with cardiopulmonary bypass.

Primary outcomes

  1. Incidence of mortality

    Time frame: 24 hours postoperatively

    Incidence of mortality was recorded.

Secondary outcomes

  1. Incidence of morbidity

    Time frame: 24 hours postoperatively

    Incidence of morbidity was recorded.

  2. Postoperative bleeding volume

    Time frame: 24 hours postoperatively.

    Total postoperative bleeding volume within the first 24 hours after surgery, measured by cumulative chest tube drainage.

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Effect of Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Apr 3, 2026
Registry last updated
Apr 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.