Skip to main content
OpenTrials
Completed

NCT Number: NCT00642070

Host Response to Urinary Tract Infection in Women

This study is being done to identify those elements of the immune response that may predispose a woman to recurrent urinary tract infection. We suspect that lesser effectiveness of certain components of the host response will lead to recurrent urinary tract infection. We will also evaluate the role that the bladder reservoir may play in recurrent urinary tract infection.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Urinary Tract Infection Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Infections Male Urogenital Diseases Urinary Tract Infections Urogenital Diseases Urologic Diseases

Age range

18 year–49 year

Sex eligibility

Female

Study type

Observational

Primary location

University of Washington/Hall Health Primary Care Center

Seattle, Washington, 98195, United States

About this study

Procedures subjects will undergo once they have read and signed the consent are:

Questions about their medical and sexual history and current symptoms of urinary tract infection. They will be asked to provide a clean catch urine sample. We will collect periurethral, vaginal and rectal swabs. Blood will collected. They will be given a diary to take home and record all episodes of sexual intercourse, contraceptive use, vaginal and urinary symptoms and medication use.

They will be given standard treatment for the current urinary tract infection. Follow-up visits will be scheduled 2 weeks,one month,two month and three month after initial visit.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female
  • Age 18-49 years
  • Able to provide written informed consent
  • diagnosis of acute cystitis with symptoms for fewer than 7 days

Exclusion criteria

  • Not pregnant or planning pregnancy in next 3 months
  • No chronic illness requiring medical supervision (e.g. diabetes mellitus)
  • No known anatomic or functional abnormalities of the urinary tract
  • No signs or symptoms suggestive of pyelonephritis (flank pain or tenderness, temperature over 100 degrees F, nausea or vomiting)

Treatment and study plan

Primary outcomes

  1. Determine elements of the immune response that may predispose a woman to recurrent urinary tract infection

    Time frame: 2017

Sponsors and collaborators

Lead sponsor

University of Washington

Other

Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Registry information

Important dates

Study start
2008
Primary completion
2012
Study completion
2012
First posted
Mar 24, 2008
Registry last updated
Jun 5, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.