Hormones and Decision Making | Clinical Trial

Key information

Conditions

Dyssocial Behavior Antisocial Personality Disorder Mental Disorders Personality Disorders

Age range

18 year–25 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 4

Primary location

Robert Josephs

Austin, Texas, 78712-1050, United States

About this study

This study will investigate the influence of reward sensitivity on cheating behavior via experimental manipulation of reward sensitivity using testosterone.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

males between 18 and 25

Exclusion criteria

recruitment will be limited to male participants between 18 and 25 years who have no current conditions that would preclude the use of testosterone. Specific exclusion criteria are:
women of all ages
males younger than 18 years and older than 25 years
self-report discomfort with ingestion of testosterone for the purpose of this study
body mass index lower than 18 or higher than 27
prior diagnosis of major depression, posttraumatic stress disorder, phobia, anxiety disorder, or other psychiatric conditions
first-degree relatives diagnosed with a psychiatric disorder
presence of a medical condition that would preclude the use of testosterone
use of medications that would preclude the use of testosterone
consumption of more than 5 cigarettes a day
current use of testosterone enhancing products, such as gels, creams, and injections

Treatment and study plan

testosterone propionate

Drug

1mg/0.1mL solution, to be administered intranasally

Other names: Testovis

0.5% cholorbutanol, saline

Drug

125 mg 0.5% cholorbutanol, 50mg saline

Primary outcomes

Measure of ethical behavior - Cheating rate defined as the Average number of 'heads' coin flips participants claim to have obtained

Time frame: 90 minutes

drug administration following by behavioral outcome. Specifically, participants will have the opportunity to predict the outcome of a series of coin flips. To obtain a measure of ethical behavior, participants will have the opportunity to cheat by over-reporting their prediction accuracy.

Sponsors and collaborators

Lead sponsor

University of Texas at Austin

Other

Registry information

Important dates

Study start: 2015
Primary completion: 2016
Study completion: 2016
First posted: Apr 29, 2021
Registry last updated: Apr 29, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed