Skip to main content
OpenTrials
Completed

NCT Number: NCT07212985

Horizontal Anterior Maxillary Ridge Augmentation Using Autogenous Ring Block Grafts Combined With Particulate Xenogeneic Bone Versus Biphasic Beta-tri-calcium Phosphate Sulphate EthOss Graft: A Clinical Study

. Group A, received ABG cylinders obtained from the chin and organic bovine bone mineral particles (Bio-Oss xenograft) along with an absorbable collagen membrane. ABG cylinders from the chin and biphasic alloplastic (EthOss) grafting material made of CS (35%) and TCP (65%) were given to Group B. CBCT scans were conducted before bone augmentation surgery, one week and 6 months postoperatively

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Implant Dentistry

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Oral and Dental Medicine, Nahda University,Taibah University

Cairo, Egypt

About this study

Two groups of forty patients participated in this prospective, controlled, randomized clinical investigation. Group A, received ABG cylinders obtained from the chin and organic bovine bone mineral particles (Bio-Oss xenograft) along with an absorbable collagen membrane. ABG cylinders from the chin and biphasic alloplastic (EthOss) grafting material made of CS (35%) and TCP (65%) were given to Group B. CBCT scans were conducted before bone augmentation surgery, one week and 6 months postoperatively

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults ≥18 years requiring implant-supported restoration in the anterior maxilla

Horizontal alveolar bone deficiency <4 mm (Cawood & Howell Class III-IV)

Satisfactory oral hygiene

No previous bone augmentation at study site

Exclusion criteria

  • Uncontrolled systemic diseases

History of head/neck irradiation or immunosuppression

Oral lesions (e.g., lichen planus)

Ongoing or recent IV bisphosphonate therapy

Untreated periodontitis or poor oral hygiene

Parafunctional habits, pregnancy, psychiatric disorders

Recent tobacco use

Treatment and study plan

Autogenous Bone Block + Xenograft + Collagen Membrane

Procedure

Autogenous chin bone block graft combined with particulate bovine xenograft (Bio-Oss, Geistlich Pharma AG) and covered with an absorbable collagen membrane (Bio-Gide).

Primary outcomes

  1. Change in horizontal alveolar ridge width

    Time frame: Baseline, 1 week, and 6 months post-surgery

Secondary outcomes

  1. Postoperative complications

    Time frame: Up to 6 months post-surgery

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Oct 8, 2025
Registry last updated
Oct 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.