Liverpool John Moores University
Liverpool, Merseyside, L3 3AF, United Kingdom
NCT Number: NCT03545802
This study aimed to use a multi-disciplinary approach to evaluate a 6-week home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
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Notify Me18 year–55 year
All sexes
Interventional
Not applicable
Liverpool, Merseyside, L3 3AF, United Kingdom
This study aimed to use a multi-disciplinary approach to evaluate a home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
Eleven individuals with type 1 diabetes (4 men/7 women; age 30±3 years; BMI 27.1±1.2 kg·m-2; V ̇O2peak 32.4±2.1 ml∙kg∙min-1; duration of type 1 diabetes 10±2 years) completed six weeks of Home-HIT. The effect of Home-HIT on V ̇O2peak, blood pressure, insulin dose and glycaemic profile was assessed pre and post-training. Adherence and ability to meet target heart rate (HR) thresholds (compliance) were monitored using a HR monitor and mobile phone application. Change in glycaemia was measured pre, post and 1h post exercise sessions throughout the six-week period. A qualitative online survey was completed post-training.
This is the first study to combine physiological outcomes with a qualitative evaluation of a training intervention in people with type 1 diabetes. Home-HIT resulted in high adherence alongside increased V ̇O2peak and decreased insulin dose. Because Home-HIT is time-efficient and removes barriers to exercise including fear of hypoglycaemia, it may represent an effective strategy to increase exercise participation in people with type 1 diabetes.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants completed 6 weeks of home-based high-intensity interval training 3 times per week
Time frame: change in baseline maximal aerobic capacity at 6 weeks
Maximal aerobic capacity was measured pre and post 6 week training intervention using a MOXUS gas analyser on a stationary cycle ergometer
Time frame: adherence to the training programme over the course of the 6 week intervention
session completion rate (adherence) was assessed
Time frame: compliance to the training programme over the course of the 6 week intervention
ability to meet target heart rates (compliance) was assessed
Time frame: change in baseline insulin sensitivity at 6 weeks
insulin dose was recorded pre and post training by participants
Time frame: change in baseline glycaemic control at 6 weeks
participants recorded their blood glucose concentrations in the first and final weeks of the intervention
Liverpool John Moores University
Other
A Multi-Disciplinary Evaluation of Home-Based High-Intensity Interval Training in People With Type 1 Diabetes: A Pilot Study
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