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Completed

NCT Number: NCT07417423

Home-Based Exercise Education in Liver Transplant Recipients

Liver transplant recipients often experience reduced physical activity levels, fatigue, and increased caregiver burden after transplantation. Structured home-based exercise education may help improve these outcomes. This study aims to evaluate the effects of brochure-based and video-based home exercise education programs on physical activity levels, fatigue, and caregiver burden in liver transplant recipients.

Participants are assigned to either a brochure-based exercise education group, a video-based exercise education group, or a control group receiving standard care. The primary objective is to determine whether structured home exercise education improves physical activity and reduces fatigue and caregiver burden compared to standard care.

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Key information

Conditions

Liver Transplantation Behavior Fatigue Motor Activity Pathological Conditions, Signs and Symptoms Physical Inactivity Sedentary Behavior Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Inonu University Turgut Ozal Medical Center

Malatya, Gaziantep, 27010, Turkey (Türkiye)

About this study

Regular physical activity is essential for improving functional capacity and quality of life in liver transplant recipients. However, many recipients experience persistent fatigue, decreased physical activity levels, and increased caregiver burden after transplantation. Structured and accessible home-based exercise education may provide a practical approach to support long-term rehabilitation in this population.

This study evaluates the effectiveness of two different home-based exercise education methods: brochure-based education and video-based education. Participants receive standardized exercise recommendations designed to promote safe and gradual increases in physical activity. The intervention period includes structured follow-up and guidance to enhance adherence. A control group receives standard post-transplant care without structured exercise education.

Outcome measures include physical activity level, fatigue severity, and caregiver burden, assessed at predefined time points during the study period. The findings of this study may contribute to the development of accessible rehabilitation strategies for liver transplant recipients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult liver transplant recipients
  • Aged 18 years or older
  • Clinically stable and cleared for participation in physical activity
  • Able to understand and follow exercise instructions
  • Provided written informed consent

Exclusion criteria

  • Presence of severe cardiovascular, respiratory, or musculoskeletal conditions that contraindicate exercise
  • Acute transplant rejection or severe post-transplant complications
  • Cognitive impairment limiting participation
  • Participation in another structured exercise program during the study period

Treatment and study plan

Home-Based Exercise Education

Behavioral

Home-Based Exercise Education consists of structured guidance designed to promote safe and progressive physical activity in liver transplant recipients. The program includes recommendations regarding exercise type, frequency, duration, and intensity appropriate for the post-transplant period. Education is delivered either through a printed brochure or instructional video materials. The content focuses on aerobic and strengthening exercises that can be performed at home without specialized equipment. Participants are encouraged to follow the prescribed exercise recommendations throughout the study period.

Brochure-Based Exercise Education (Experimental)

Behavioral

Participants receive structured home-based exercise education delivered through a printed brochure specifically developed for liver transplant recipients. The brochure includes written instructions and illustrations describing aerobic and strengthening exercises, along with recommendations for frequency, duration, intensity, and progression. The material is designed to enable participants to independently perform safe and gradual physical activity at home throughout the study period.

Primary outcomes

  1. Physical Activity Level

    Time frame: Baseline and end of intervention (8 weeks)

    International Physical Activity Questionnaire (IPAQ). Physical activity is expressed as MET-minutes per week calculated from activity intensity and duration. Scores range from 0 to >3000 MET-min/week, with higher values indicating higher physical activity level.

Sponsors and collaborators

Lead sponsor

Hasan Kalyoncu University

Other

Registry information

Official study title

The Effect of Brochure- and Video-Based Home Exercise Education on Physical Activity, Fatigue, and Caregiver Burden in Liver Transplant Recipients: A Randomized Controlled Trial

Acronym: Liv (Liver)

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Feb 18, 2026
Registry last updated
Feb 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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