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OpenTrials
Completed

NCT Number: NCT02167191

HIT in the Healthy Elderly Population

It is widely known that exercise improves general fitness and that fitter patients recover more easily from illness and surgery. Conversely, unfit patients have a significantly higher morbidity and mortality after surgery and a longer inpatient stay. This will become increasingly important in an aging population as baseline fitness generally declines with age.

One method of improving cardiovascular fitness is by using low intensity endurance training programmes, a disadvantage of these it that they can take several months to show improvement. High intensity interval training (HIT) programmes that use short episodes of high intensity exercise have also been shown to improve fitness. These HIT programmes have also shown improvement in functional capacity and quality of life in patients with chronic disease. An advantage of HIT is that improvements in fitness may occur in a shorter time than traditional endurance training. It is also known that HIT can give superior gains over endurance training.

The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by a 2ml/kg/min increase in VO2peak, can be achieved within 31 days via a HIT programme, in a group of healthy elderly volunteers.

As a secondary aim we will assess whether this programme would be acceptable to the group studied, through determination of subject compliance and adherence to the training programme.

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Key information

Age range

60 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Nottingham

Derby, Derbyshire, DE22 3DT, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Good health
  • Male and female
  • 60 -75 years old

Exclusion criteria

  • Uncontrolled hypertension (BP > 140/100)
  • Angina
  • Heart failure (NYHA class III/IV)
  • Cardiac arrthymias
  • Right to left cardiac shunt
  • Recent cardiac event
  • Previous stroke/TIA
  • Aneurysm (large vessel or intracranial)
  • Severe respiratory disease including pulmonary hypertension
  • COPD/asthma with an FEV1 less than 1.5 l
  • Inclusion into any other research study in the last three months which involved: taking a drug; being paid a disturbance allowance; having an invasive procedure or exposure to ionising radiation

Treatment and study plan

HIT

Behavioral

12 sessions of HIT exercise in 31 days on a stationary cycle ergometer

Primary outcomes

  1. VO2 peak

    Time frame: 31 days

Sponsors and collaborators

Lead sponsor

University of Nottingham

Other

Registry information

Official study title

Determining the Effectiveness of a High Intensity Interval Training Exercise Programme in the Healthy, Elderly Population

Acronym: HIT

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Jun 18, 2014
Registry last updated
Oct 1, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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