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Active, Not Recruiting

NCT Number: NCT03829059

Histological/ Immunohistological and Molecularpathological Types of Epulides and Central Giant Cell Lesions of the Jaws

This retrospective study will evaluate the patient collective of the Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health and of the Division of Cranio-Maxillofacial Surgery at the Medical University Graz concerning the frequency of epulis/giant cell lesion or underlying differential diagnoses and immunophenotypes as well as the resulting treatment methods and their success and compare these with international results

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Epulis Gingival Diseases Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

7 year–95 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Medical University

Graz, 8036, Austria

About this study

Different histopathological differential diagnoses can underlay the clinical presentation of an epulis. Often the immunophenotype of these lesions is of particular importance. This also holds for the the central giant cell lesion.

This study will evaluate the patient collective of the Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health and of the Division of Cranio-Maxillofacial Surgery at the Medical University Graz concerning the frequency of epulis/giant cell lesion or underlying differential diagnoses and immunophenotypes as well as the resulting treatment methods and their success and compare these with international results.

This is a retrospective study using electronic patient records, written records, operative reports of the Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health and of the Division of Cranio-Maxillofacial Surgery at the Medical University Graz in the period from 1986 to March 2018. It is intended to gather the data within 12 months and analyze statistically subsequently.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • existence of a medical history and a histopathological finding of the surgical specimen
  • patients treated in the outpatient clinic for diseases of oral mucosa of the Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health and of the Division of Cranio-Maxillofacial Surgery at the Medical University Graz between 1986 and March 2018

Exclusion criteria

  • absence of a medical history or a histopathological finding.

Treatment and study plan

Primary outcomes

  1. Frequency of histological pathological differential diagnoses.

    Time frame: time period of evaluation from 1986 to March 2018

  2. Frequency of immunohistochemical pathological differential diagnoses.

    Time frame: time period: from 1986 to March 2018

  3. Frequency of molecular pathological differential diagnoses.

    Time frame: time period from 1986 to March 2018

Secondary outcomes

  1. Frequency of recurrences

    Time frame: time period from 1986 to March 2018

    depending on differential diagnoses and therapy

Sponsors and collaborators

Lead sponsor

Medical University of Graz

Other

Registry information

Official study title

Retrospective Clinico-pathological Examinations on Different Histological/ Immunohistological and Molecularpathological Types of Epulides and Central Giant Cell Lesions of the Jaws

Important dates

Study start
2018
Primary completion
2026
Study completion
2026
First posted
Feb 4, 2019
Registry last updated
Nov 20, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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