HISTOACRYL: A Study of Its Efficacy in Final Scar Formation

Inclusion criteria

• Age: Younger than 21
• Gender: Females only. Given the nature of the procedures, as well as our clinical experience, we cannot anticipate recruiting enough male patients to be able to evaluate them as a subgroup. Since there may be differences in distributions of measures, to keep the groups more homogeneous we plan to recruit only females from the outset. Having either:
• Reduction Mammoplasty or mastopexy patients:

• Patients who present to the plastic surgery clinic and are scheduled for breast procedures will be recruited and consented by a clinical studies co-ordinator.
• This will include patients undergoing a standard Wise pattern reduction mammoplasty (reduction and lift) or a standard Wise pattern mastopexy (lift only). See exclusion criteria below.
• Abdominoplasty or panniculectomy patients:

• Patients who present to the plastic surgery clinic and are scheduled for abdominal procedures will be recruited and consented by a clinical studies coordinator. See exclusion criteria below.

Exclusion criteria

• Though women of childbearing age will be allowed to participate in this study, no pregnant patients will be enrolled.
• Patients with any factors that may have an adverse effect on wound healing:

• previous hypertrophic scars or keloid
• known vitamin C deficiency
• known zinc deficiency
• smoking
• steroid use
• known connective tissue disorder
• hypoalbuminemia
• any factor not listed that the attending consultant seeing the patient feels would adversely effect wound healing.
• Patients who have a known sensitivity to adhesives