Accelerated medical clearance and surgery
OtherRapid medical clearance with targeted arrival to the operating room within 6 hours of diagnosis of a hip fracture requiring surgical repair.
NCT Number: NCT02027896
HIP ATTACK is an international randomized controlled trial of 3000 patients with a hip fracture that requires a surgical intervention. This trial will determine the effect of accelerated medical clearance and accelerated surgery compared to standard care on the 90-day risk of mortality and major perioperative complication (i.e., a composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding).
Looking for future studies?
Notify Me45 year and older
All sexes
Interventional
Not applicable
Cliniques Universitaires Saint-Luc, Brussels, Belgium
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Rapid medical clearance with targeted arrival to the operating room within 6 hours of diagnosis of a hip fracture requiring surgical repair.
Time frame: 90 days
Composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding
Time frame: 90 days
All-cause mortality
Time frame: 90 days and 1 year
Death due to all causes
Time frame: 90 days and 1 year
Death due to vascular cause
Time frame: 90 days and 1 year
Death due to non-vascular cause
Time frame: 90 days and 1 year
Myocardial infarction
Time frame: 90 days and 1 year
i.e., percutaneous coronary intervention [PCI] or coronary artery bypass grafting [CABG] surgery
Time frame: 90 days and 1 year
New congestive heart failure
Time frame: 90 days
New clinically important atrial fibrillation
Time frame: 30 days and 1 year
Nonfatal cardiac arrest
Time frame: 90 days and 1 year
Stroke
Time frame: 90 days and 1 year
Peripheral arterial thrombosis
Time frame: 90 days and 1 year
Pulmonary embolism
Time frame: 90 days and 1 year
Deep venous thrombosis
Time frame: 90 days and 1 year
Pneumonia
Time frame: 90 days and 1 year
Sepsis
Time frame: 90 days
Infection
Time frame: 90 days
Life-threatening bleeding
Time frame: 90 days
Major bleeding
Time frame: 90 days and 1 year
New acute renal failure requiring dialysis
Time frame: 90 days and 1 year
Peri-prosthetic fracture
Time frame: 90 days and 1 year
Prosthetic hip dislocation
Time frame: 90 days and 1 year
Implant failure
Time frame: 30 days and 1 year
Hip re-operation
Time frame: 90 days
Time to first mobilization
Time frame: 90 days
Length of hospital stay
Time frame: 90 days
Length of critical care stay
Time frame: 90 days
Length of rehabilitation stay
Time frame: 90 days and 1 year
New residence in a nursing home
Time frame: 30 days and 1 year
Functional Independence Measure (FIM™)
Time frame: 30 days and 1 year
SF-36 score
Time frame: 7 days
Delirium within 7 days of randomization
Time frame: 90 days and 1 year
Hospital readmission
Time frame: 90 days
New pressure ulcers
Time frame: 30 days
Incisional pain
Time frame: 1 year
Chronic incisional pain
Time frame: 90 Day
Acute Kidney Injury
Time frame: 1 Year
Acute Kidney Injury
Time frame: 30 Days
Mortality and Institutionalization status of dependents
Time frame: 1 Year
Mortality and Institutionalization status of dependents
Time frame: 90 Days and 1 Year
Economic Analysis
Time frame: 2, 5, 10 Years
Health System Utilization, Long Term Follow up
McMaster University
Other
Acronym: HIP ATTACK
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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