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NCT Number: NCT06673381

High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome

assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag faculty of medicine

Sohag, Egypt

Location status: Recruiting

Location contact

Amira Elbasuony

CONTACT

01113695925

About this study

Observational study conducted at coronary care unit(CCU) in sohag university hospital It included patients with ACS diagnosed according to AHA/ACCF guidelines (according to symptoms, ECG findings and serum troponin levels), who had admitted to the CCU.

Venous blood samples were instantly collected on admission to the hospital. hs-CRP , serum albumin level were measured.

hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR) In-hospital MACE was regarded as the end point of our study. It was defined as acute heart failure, cardiogenic shock, reinfarction, all-cause death, serious arrhythmia and cardiac death

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients aged 18 Year or older presented by ACS not candidet for primary percutaneus coronary intervention ( PCI ) .

Exclusion criteria

  • • Patients aged < 18 years old
  • Patients who have eGFR <60 ml/kg /m2
  • Patients who have malignancies
  • Patients who have chronic heart failure (NYHA class >II)
  • Pateints who have chronic liver disease
  • Patients who have nephrotic syndrome
  • Patients who have acute cerebrovascular stroke
  • Pregnant women
  • Patients who have recent infection

Treatment and study plan

Primary outcomes

  1. assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in acute coronary syndrom patients

    Time frame: at time of admission in hospital

    Venous blood samples were collected on admission to the hospital. hs-CRP , serum albumin level were measured.

    hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR)

Study contacts

Contact information is provided by the study sponsor or research team.

Amira Elbasuony, resident

CONTACT

[email protected]

01113695925

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Prediction of Acute Coronary Syndrome In-hospital Major Adverse Cardiovascular Events by High Sensitivity C- Reactive Protein to Albumin Ratio

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Nov 4, 2024
Registry last updated
Nov 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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